Journal
CHEMICAL COMMUNICATIONS
Volume 54, Issue 65, Pages 9027-9030Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c8cc04481c
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Funding
- National Natural Science Foundation of China [21390410, 21621003, 21727813, 51473086]
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A novel photoluminescence lifetime probe (Ir-TB) has been developed for the detection and imaging of hCE2 in living cells. A large lifetime increase by around 300 ns after the enzymatic reaction makes it an ideal tool to distinguish hCE2-hydrolyzed probes from those non-hydrolyzed ones via PLIM for the first time.
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