Journal
CHEMICAL COMMUNICATIONS
Volume 54, Issue 43, Pages 5422-5425Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c8cc01053f
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Funding
- MIUR (Ministero Istruzione, Universita e Ricerca), PRIN [2012A7LMS3]
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Protein fibrillation is involved in many serious diseases, and protein oligomers are proved to be precursors of amyloid fibrils. NMR and QCMD experiments allowed us to establish that the interaction between citrate-stabilized gold nanoparticles and a paradigmatic amyloidogenic protein, 2-microglobulin, is able to interfere with protein association into oligomers.
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