Journal
CHEMICAL COMMUNICATIONS
Volume 54, Issue 49, Pages 6412-6415Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c8cc03475c
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Funding
- National Natural Science Foundation of China [21472121]
- State Key Laboratory of Applied Organic Chemistry, Lanzhou University
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An unusual cascade reaction of isocyanide and enynone using Yb/Ag cooperative catalysis as a key step has been disclosed. The present strategy enables the double isocyanide insertion and subsequent 5-endo-dig cyclization, thus providing a quick access to structurally complex pyrrole-fused heterocycles.
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