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Note: Only part of the references are listed.UniProt: the universal protein knowledgebase
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BIOCHEMICAL JOURNAL (2016)
miRpower: a web-tool to validate survival-associated miRNAs utilizing expression data from 2178 breast cancer patients
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BREAST CANCER RESEARCH AND TREATMENT (2016)
CD45 Phosphatase Inhibits STAT3 Transcription Factor Activity in Myeloid Cells and Promotes Tumor-Associated Macrophage Differentiation
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MiR-1181 inhibits stem cell-like phenotypes and suppresses SOX2 and STAT3 in human pancreatic cancer
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CANCER LETTERS (2015)
Signal transducer and activator of transcription 3-mediated CD133 up-regulation contributes to promotion of hepatocellular carcinoma
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Dan Lu et al.
NATURE IMMUNOLOGY (2015)
p63 sustains self-renewal of mammary cancer stem cells through regulation of Sonic Hedgehog signaling
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Bcl3 Bridges LIF-STAT3 to Oct4 Signaling in the Maintenance of Naive Pluripotency
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CELLULAR ONCOLOGY (2015)
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ONCOGENE (2015)
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BMC GENOMICS (2014)
Loss of Androgen Receptor Expression Promotes a Stem-like Cell Phenotype in Prostate Cancer through STAT3 Signaling
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CANCER RESEARCH (2014)
VEGF-Mediated Angiogenesis Links EMT-Induced Cancer Stemness to Tumor Initiation
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CANCER RESEARCH (2014)
A Noncanonical Frizzled2 Pathway Regulates Epithelial-Mesenchymal Transition and Metastasis
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CELL (2014)
STAT3 activation in HER2-overexpressing breast cancer promotes epithelial-mesenchymal transition and cancer stem cell traits
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INTERNATIONAL JOURNAL OF ONCOLOGY (2014)
Critical Role for Lysine 685 in Gene Expression Mediated by Transcription Factor Unphosphorylated STAT3
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JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome
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JOURNAL OF PROTEOMICS (2014)
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NATURE REVIEWS DRUG DISCOVERY (2014)
STAT3 and HIF1α cooperatively activate HIF1 target genes in MDA-MB-231 and RCC4 cells
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Correction: The Cellular Prion Protein PrPc Is Involved in the Proliferation of Epithelial Cells and in the Distribution of Junction-Associated Proteins
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PLoS One (2014)
IL-6/STAT3 promotes regeneration of airway ciliated cells from basal stem cells
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
STAT3 Signaling Is Activated Preferentially in Tumor-Initiating Cells in Claudin-Low Models of Human Breast Cancer
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STEM CELLS (2014)
MiR-7, Inhibited Indirectly by LincRNA HOTAIR, Directly Inhibits SETDB1 and Reverses the EMT of Breast Cancer Stem Cells by Downregulating the STAT3 Pathway
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STAT3 Phosphorylation at Tyrosine 705 and Serine 727 Differentially Regulates Mouse ESC Fates
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BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2013)
Phosphorylation of EZH2 Activates STAT3 Signaling via STAT3 Methylation and Promotes Tumorigenicity of Glioblastoma Stem-like Cells
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Sox2 Cooperates with Inflammation-Mediated Stat3 Activation in the Malignant Transformation of Foregut Basal Progenitor Cells
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JOURNAL OF INTERFERON AND CYTOKINE RESEARCH (2012)
Constitutive activation of STAT3 is predictive of poor prognosis in human gastric cancer
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JOURNAL OF MOLECULAR MEDICINE-JMM (2012)
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MODERN PATHOLOGY (2012)
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PLOS ONE (2012)
microRNA-124 Regulates Cardiomyocyte Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells Via Targeting STAT3 Signaling
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STEM CELLS (2012)
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BREAST CANCER RESEARCH (2012)
STAT3 signaling pathway is necessary for cell survival and tumorsphere forming capacity in ALDH+/CD133+ stem cell-like human colon cancer cells
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BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
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BIOCHEMICAL PHARMACOLOGY (2011)
Nonreceptor Tyrosine Kinase BMX Maintains Self-Renewal and Tumorigenic Potential of Glioblastoma Stem Cells by Activating STAT3
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JOURNAL OF CLINICAL INVESTIGATION (2011)
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PLOS ONE (2011)
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INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2011)
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BLOOD (2010)
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Stat3 Activation Is Limiting for Reprogramming to Ground State Pluripotency
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EXPERIMENTAL CELL RESEARCH (2010)
Mammalian target of rapamycin regulates murine and human cell differentiation through STAT3/p63/Jagged/Notch cascade
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STAT3-induced S1PR1 expression is crucial for persistent STAT3 activation in tumors
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NATURE MEDICINE (2010)
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NEW ENGLAND JOURNAL OF MEDICINE (2010)
EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer
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ONCOGENE (2010)
Reversible methylation of promoter-bound STAT3 by histone-modifying enzymes
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
TGF-β Increases Glioma-Initiating Cell Self-Renewal through the Induction of LIF in Human Glioblastoma
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Toll-like Receptor 9 Activation of Signal Transducer and Activator of Transcription 3 Constrains Its Agonist-Based Immunotherapy
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CANCER RESEARCH (2009)
Signal Transducer and Activator of Transcription 3 (STAT3) Mediates Amino Acid Inhibition of Insulin Signaling through Serine 727 Phosphorylation
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JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Acetylation and activation of STAT3 mediated by nuclear translocation of CD44
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Effects of signal transducer and activator of transcription (STAT) genes STAT1 and STAT3 genotypic combinations on fertilization and embryonic survival rates in Holstein cattle
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Mitochondrial STAT3 Supports Ras-Dependent Oncogenic Transformation
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NATURE REVIEWS CANCER (2009)
The p53 homologue ΔNp63α interacts with the nuclear factor-κB pathway to modulate epithelial cell growth
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CANCER RESEARCH (2008)
Activation of signal transducer and activator of transcription 3 through a phosphomimetic serine 727 promotes prostate tumorigenesis independent of tyrosine 705 phosphorylation
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CANCER RESEARCH (2008)
The epithelial-mesenchymal transition generates cells with properties of stem cells
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CELL (2008)
Transcriptional activity of the ΔNp63 promoter is regulated by STAT3
Wing-Keung Chu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Sorafenib inhibits signal transducer and activator of transcription 3 signaling associated with growth arrest and apoptosis of medulloblastomas
Fan Yang et al.
MOLECULAR CANCER THERAPEUTICS (2008)
Nanog maintains pluripotency of mouse embryonic stem cells by inhibiting NFκB and cooperating with Stat3
Josema Torres et al.
NATURE CELL BIOLOGY (2008)
Progenitor/stem cells give rise to liver cancer due to aberrant TGF-β and IL-6 signaling
Yi Tang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Activation of the PTEN/mTOR/STAT3 pathway in breast cancer stem-like cells is required for viability and maintenance
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Cleavage of the transactivation-inhibitory domain of p63 by caspases enhances apoptosis
Berna S. Sayan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Unphosphorylated STAT3 accumulates in response to IL-6 and activates transcription by binding to NF kappa B
Jinbo Yang et al.
GENES & DEVELOPMENT (2007)
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
Kazutoshi Takahashi et al.
CELL (2006)
Notch signalling regulates stem cell numbers in vitro and in vivo
Andreas Androutsellis-Theotokis et al.
NATURE (2006)
Unique effects of Stat3 on the early phase of hematopoietic stem cell regeneration
Yang-Jo Chung et al.
BLOOD (2006)
Non-cell-autonomous action of STAT3 in maintenance of neural precursor cells in the mouse neocortex
Takeshi Yoshimatsu et al.
DEVELOPMENT (2006)
BCR-ABL activates STAT3 via JAK and MEK pathways in human cells
Paul Coppo et al.
BRITISH JOURNAL OF HAEMATOLOGY (2006)
Phosphorylation of STAT3 Serine-727 by cyclin-dependent kinase 1 is critical for nocodazole-induced mitotic arrest
Xiaoqing Shi et al.
BIOCHEMISTRY (2006)
Dual regulation of the ΔNp63 transcriptional activity by ΔNp63 in human nasopharyngeal carcinoma cell
WK Chu et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Reactivation of developmentally expressed p63 isoforms predisposes to tumor development and progression
MI Koster et al.
CANCER RESEARCH (2006)
Regulation of dendritic cell differentiation and antitumor immune response in cancer by pharmacologic-selective inhibition of the Janus-activated kinase 2/signal transducers and activators of transcription 3 pathway
Y Nefedova et al.
CANCER RESEARCH (2005)
Suppression of Stat3 promotes neurogenesis in cultured neural stem cells
F Gu et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2005)
STAT3 nuclear import is independent of tyrosine phosphorylation and mediated by importin-α3
L Liu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Activation of Stat3 sequence-specific DNA binding and transcription by p300/CREB-binding protein-mediated acetylation
R Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
LIF/STAT3 controls ES cell self-renewal and pluripotency by a Myc-dependent mechanism
P Cartwright et al.
DEVELOPMENT (2005)
Stat3 dimerization regulated by reversible acetylation of a single lysine residue
ZL Yuan et al.
SCIENCE (2005)
Immunoaffinity profiling of tyrosine phosphorylation in cancer cells
J Rush et al.
NATURE BIOTECHNOLOGY (2005)
The STAT3 isoforms and have unique and specific functions
D Maritano et al.
NATURE IMMUNOLOGY (2004)
Proteolytic conversion of STAT3α to STAT3γ in human neutrophils -: Role of granule-derived serine proteases
T Kato et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Selective activation of STAT3 in human monocytes stimulated by G-CSF:: implication in inhibition of LPS-induced TNF-α production
S Nishiki et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2004)
Hes binding to STAT3 mediates crosstalk between Notch and JAK-STAT signalling
S Kamakura et al.
NATURE CELL BIOLOGY (2004)
Maintenance of pluripotency in human embryonic stem cells is STAT3 independent
RK Humphrey et al.
STEM CELLS (2004)
LIF/STAT3 signaling fails to maintain self-renewal of human embryonic stem cells
L Daheron et al.
STEM CELLS (2004)
Serine phosphorylation of STAT3 is essential for Mcl-1 expression and macrophage survival
HT Liu et al.
BLOOD (2003)
Differential expression of p63 isoforms in normal tissues and neoplastic cells
K Nylander et al.
JOURNAL OF PATHOLOGY (2002)
Activation of STAT3 by the Src family kinase Hck requires a functional SH3 domain
SJ Schreiner et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
STATs: Transcriptional control and biological impact
DE Levy et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2002)
TAp63γ (p51A) and dNp63α (p73L), two major isoforms of the p63 gene, exert opposite effects on the vascular endothelial growth factor (VEGF) gene expression
M Senoo et al.
ONCOGENE (2002)
The p53 family member genes are involved in the notch signal pathway
Y Sasaki et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Differential expression and phosphorylation of distinct STAT3 proteins during granulocytic differentiation
DL Hevehan et al.
BLOOD (2002)
Stem cells, cancer, and cancer stem cells
T Reya et al.
NATURE (2001)
p63 identifies keratinocyte stem cells
G Pellegrini et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130
SE Nicholson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Mechanism of STAT3 activation by insulin-like growth factor I receptor
CS Zong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
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