4.8 Article

Setd2 deficiency impairs hematopoietic stem cell self-renewal and causes malignant transformation

Related references

Note: Only part of the references are listed.
Article Multidisciplinary Sciences

Intragenic DNA methylation prevents spurious transcription initiation

Francesco Neri et al.

NATURE (2017)

Article Biochemistry & Molecular Biology

Dual Chromatin and Cytoskeletal Remodeling by SETD2

In Young Park et al.

Article Medicine, General & Internal

Genomic Classification and Prognosis in Acute Myeloid Leukemia

Elli Papaemmanuil et al.

NEW ENGLAND JOURNAL OF MEDICINE (2016)

Article Hematology

Ribosomopathies and the paradox of cellular hypo- to hyperproliferation

Kim De Keersmaecker et al.

BLOOD (2015)

Article Biochemistry & Molecular Biology

Loss of BAP1 function leads to EZH2-dependent transformation

Lindsay M. LaFave et al.

NATURE MEDICINE (2015)

Article Multidisciplinary Sciences

DNA-damage-induced differentiation of leukaemic cells as an anti-cancer barrier

Margarida A. Santos et al.

NATURE (2014)

Article Genetics & Heredity

Identification of functional cooperative mutations of SETD2 in human acute leukemia

Xiaofan Zhu et al.

NATURE GENETICS (2014)

Article Multidisciplinary Sciences

Genomic landscape of CD34+ hematopoietic cells in myelodysplastic syndrome and gene mutation profiles as prognostic markers

Lan Xu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Article Biochemistry & Molecular Biology

Xist RNA Is a Potent Suppressor of Hematologic Cancer in Mice

Eda Yildirim et al.

Article Medicine, Research & Experimental

Myelodysplastic syndromes are induced by histone methylation-altering ASXL1 mutations

Daichi Inoue et al.

JOURNAL OF CLINICAL INVESTIGATION (2013)

Article Immunology

Deletion of Asxl1 results in myelodysplasia and severe developmental defects in vivo

Omar Abdel-Wahab et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2013)

Article Multidisciplinary Sciences

Mutational landscape and significance across 12 major cancer types

Cyriac Kandoth et al.

NATURE (2013)

Article Medicine, General & Internal

Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia

Timothy J. Ley et al.

NEW ENGLAND JOURNAL OF MEDICINE (2013)

Article Biochemistry & Molecular Biology

Histone methyltransferase SETD2 coordinates FACT recruitment with nucleosome dynamics during transcription

Silvia Carvalho et al.

NUCLEIC ACIDS RESEARCH (2013)

Article Multidisciplinary Sciences

Set2 methylation of histone H3 lysine 36 suppresses histone exchange on transcribed genes

Swaminathan Venkatesh et al.

NATURE (2012)

Article Multidisciplinary Sciences

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

Jinghui Zhang et al.

NATURE (2012)

Article Medicine, General & Internal

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

Marco Gerlinger et al.

NEW ENGLAND JOURNAL OF MEDICINE (2012)

Article Multidisciplinary Sciences

Loss of the Tumor Suppressor BAP1 Causes Myeloid Transformation

Anwesha Dey et al.

SCIENCE (2012)

Article Biochemistry & Molecular Biology

AKT/FOXO Signaling Enforces Reversible Differentiation Blockade in Myeloid Leukemias

Stephen M. Sykes et al.

Article Medicine, General & Internal

Clinical Effect of Point Mutations in Myelodysplastic Syndromes

Rafael Bejar et al.

NEW ENGLAND JOURNAL OF MEDICINE (2011)

Article Cell & Tissue Engineering

Regulation of the HIF-1α Level Is Essential for Hematopoietic Stem Cells

Keiyo Takubo et al.

CELL STEM CELL (2010)

Article Multidisciplinary Sciences

Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes

Gillian L. Dalgliesh et al.

NATURE (2010)

Article Multidisciplinary Sciences

Histone H3 lysine 36 methyltransferase Hypb/Setd2 is required for embryonic vascular remodeling

Ming Hu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Multidisciplinary Sciences

Regulation of Alternative Splicing by Histone Modifications

Reini F. Luco et al.

SCIENCE (2010)

Article Oncology

Clinical Relevance of Bone Marrow Fibrosis and CD34-Positive Cell Clusters in Primary Myelodysplastic Syndromes

Matteo Giovanni Della Porta et al.

JOURNAL OF CLINICAL ONCOLOGY (2009)

Review Hematology

Myelodysplastic syndromes

Stephen D. Nimer

BLOOD (2008)

Article Biochemistry & Molecular Biology

Dynamic histone H3 methylation during gene induction: HYPB/Setd2 mediates all H3K36 trimethylation

John W. Edmunds et al.

EMBO JOURNAL (2008)

Review Biochemistry & Molecular Biology

Epigenetic regulation of normal and malignant hematopoiesis

K. L. Rice et al.

ONCOGENE (2007)

Article Biochemistry & Molecular Biology

Compensation and specificity of function within the E2F family

L-J Kong et al.

ONCOGENE (2007)

Article Biochemistry & Molecular Biology

Identification and characterization of a novel human histone H3 lysine 36-specific methyltransferase

XJ Sun et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Biochemistry & Molecular Biology

Methylation of histone H3 by Set2 in Saccharomyces cerevisiae is linked to transcriptional elongation by RNA polymerase II

NJ Krogan et al.

MOLECULAR AND CELLULAR BIOLOGY (2003)

Article Biochemistry & Molecular Biology

The Set2 histone methyltransferase functions through the phosphorylated carboxyl-terminal domain of RNA polymerase II

B Li et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Biochemistry & Molecular Biology

Association of the histone methyltransferase Set2 with RNA polymerase II plays a role in transcription elongation

JX Li et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Review Biochemistry & Molecular Biology

Tobacco smoke carcinogens, DNA damage and p53 mutations in smoking-associated cancers

GP Pfeifer et al.

ONCOGENE (2002)

Review Medicine, General & Internal

Medical progress: Myelofibrosis with myeloid metaplasia.

A Tefferi

NEW ENGLAND JOURNAL OF MEDICINE (2000)