4.8 Editorial Material

Dietary Fructose Metabolism By Splanchnic Organs: Size Matters

Journal

CELL METABOLISM
Volume 27, Issue 3, Pages 483-485

Publisher

CELL PRESS
DOI: 10.1016/j.cmet.2018.02.013

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Funding

  1. Physiological Society
  2. Rank Prize Funds
  3. European Society for Clinical Nutrition and Metabolism
  4. Lucozade Ribena Suntory
  5. Arla Foods Ingredients
  6. Kenniscentrum Suiker Voeding
  7. GlaxoSmithKline

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The initial metabolism of fructose is thought to primarily take place in the liver. Using stable isotope labeling combined with tissue and arterio-venous sampling, Jang et al. (2018) demonstrate that in mice, the small intestine is the primary site of fructose metabolism. This raises important questions about fructose handling in humans.

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