Journal
CELL
Volume 173, Issue 3, Pages 538-540Publisher
CELL PRESS
DOI: 10.1016/j.cell.2018.03.077
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Extensive multi-regional whole-genome and -exome sequencing performed in tumors from patients with localized, as well as metastatic, clear cell renal cell carcinoma provides a comprehensive description of the tumor origin, intratumoral heterogeneity, evolution, and route to metastasis, laying the foundation for the development of precision clinical management.
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