Journal
CELL
Volume 172, Issue 1-2, Pages 8-10Publisher
CELL PRESS
DOI: 10.1016/j.cell.2017.12.029
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Funding
- Ministry of Education, Culture, Science, Sports, and Technology (MEXT) of Japan [JP16H06429, JP16K21723, JP16H06430]
- Japan Agency for Medical Research and Development (AMED) [JP17fm0208014]
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Arc, a master regulator of synaptic plasticity, contains sequence elements that are evolutionarily related to retrotransposon Gag genes. Two related papers in this issue of Cell show that Arc retains retroviral-like capsid-forming ability and can transmit mRNA between cells in the nervous system, a process that may be important for synaptic function.
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