Journal
CARDIOVASCULAR PATHOLOGY
Volume 36, Issue -, Pages 25-29Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.carpath.2018.06.001
Keywords
Mesothelial/monocytic incidental cardiac excrescences; MICE; Histiocytic proliferations; Immunohistochemistry; Adhesion molecules; CD 31
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Mesothelial/monocytic incidental cardiac excrescence (MICE) is a benign lesion composed of histiocytes and mesothelial cells, usually found during cardiac surgery. To date, no more than 50 cases are reported in literature, and pathogenesis is still unclear even if different theories have been proposed. Here we report a case of MICE encountered during aortic valve replacement with typical histological features and extensive immunohistochemical investigation. To date, little information is available about the pathogenesis of MICE. We review the current literature focusing on the role of adhesion molecules such as CD 31. (c) 2018 Elsevier Inc. All rights reserved.
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