4.8 Editorial Material

Glucose Metabolism in Cancer: The Saga of Pyruvate Kinase Continues

Journal

CANCER CELL
Volume 33, Issue 3, Pages 337-339

Publisher

CELL PRESS
DOI: 10.1016/j.ccell.2018.02.008

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Funding

  1. NIGMS NIH HHS [T32 GM007105] Funding Source: Medline
  2. NIH HHS [S10 OD018164] Funding Source: Medline

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Altered glucose metabolism is common in cancer. In this issue of Cancer Cell, Morita et al. report new mouse models that express specific isoforms of pyruvate kinase to study glycolysis in tumors. They report several unanticipated findings that challenge current ideas in cancer metabolism.

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