Journal
CANADIAN JOURNAL OF CARDIOLOGY
Volume 34, Issue 6, Pages 717-725Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.cjca.2018.01.018
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Funding
- Canadian Institutes of Health Research [MOP-97943]
- Fondation de l'Institut de Cardiologie de Montreal
- Carolyn and Richard Renaud Research Chair in Heart Failure of the Montreal Heart Institute
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Although it is widely recognized that inflammation plays a critical role in the development and pathology of heart failure (HF), very little is known about the involvement of one of the most abundant immune cells in the blood, a primary immune response cell: the neutrophil. This review summarizes the current literature on the role of subclinical inflammation, with a focus on the neutrophil in the pathophysiology of the HF syndrome. Some emerging therapeutic strategies are also discussed.
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