4.6 Review

Patient-derived organoid models help define personalized management of gastrointestinal cancer

Related references

Note: Only part of the references are listed.
Article Oncology

Universal Genomic Testing: The next step in oncological decision-making or a dead end street?

Julian Walter Holch et al.

EUROPEAN JOURNAL OF CANCER (2017)

Article Multidisciplinary Sciences

Biliary epithelial injury-induced regenerative response by IL-33 promotes cholangiocarcinogenesis from peribiliary glands

Hayato Nakagawa et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Article Multidisciplinary Sciences

Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade

Dung T. Le et al.

SCIENCE (2017)

Article Multidisciplinary Sciences

Lipid-mediated Wnt protein stabilization enables serum-free culture of human organ stem cells

Nesrin Tuysuz et al.

NATURE COMMUNICATIONS (2017)

Article Oncology

Personalized In Vitro and In Vivo Cancer Models to Guide Precision Medicine

Chantal Pauli et al.

CANCER DISCOVERY (2017)

Article Oncology

Cancer Statistics, 2017

Rebecca L. Siegel et al.

CA-A CANCER JOURNAL FOR CLINICIANS (2017)

Article Oncology

Colorectal cancer statistics, 2017

Rebecca L. Siegel et al.

CA-A CANCER JOURNAL FOR CLINICIANS (2017)

Review Gastroenterology & Hepatology

Gastric Cancer in the Era of Precision Medicine

Xi Liu et al.

CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY (2017)

Article Multidisciplinary Sciences

Designer matrices for intestinal stem cell and organoid culture

Nikolce Glorevski et al.

NATURE (2016)

Article Multidisciplinary Sciences

Tissue-specific mutation accumulation in human adult stem cells during life

Francis Blokzijl et al.

NATURE (2016)

Review Oncology

Modeling Pancreatic Cancer with Organoids

Lindsey A. Baker et al.

TRENDS IN CANCER (2016)

Article Biochemistry & Molecular Biology

Long-Term Culture of Genome-Stable Bipotent Stem Cells from Adult Human Liver

Meritxell Huch et al.

Article Biochemistry & Molecular Biology

Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients

Marc van de Wetering et al.

Article Biochemistry & Molecular Biology

Organoid Models of Human and Mouse Ductal Pancreatic Cancer

Sylvia F. Boj et al.

Review Oncology

Translational Implications of Tumor Heterogeneity

Mariam Jamal-Hanjani et al.

CLINICAL CANCER RESEARCH (2015)

Article Gastroenterology & Hepatology

In Vitro Expansion of Human Gastric Epithelial Stem Cells and Their Responses to Bacterial Infection

Sina Bartfeld et al.

GASTROENTEROLOGY (2015)

Review Oncology

Metastatic Colorectal Cancer: Current State and Future Directions

Marwan G. Fakih

JOURNAL OF CLINICAL ONCOLOGY (2015)

Article Surgery

Two Thousand Consecutive Pancreaticoduodenectomies

John L. Cameron et al.

JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS (2015)

Article Multidisciplinary Sciences

Sequential cancer mutations in cultured human intestinal stem cells

Jarno Drost et al.

NATURE (2015)

Article Multidisciplinary Sciences

Whole genomes redefine the mutational landscape of pancreatic cancer

Nicola Waddell et al.

NATURE (2015)

Article Biochemistry & Molecular Biology

Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients

Giulia Siravegna et al.

NATURE MEDICINE (2015)

Article Biochemistry & Molecular Biology

Modeling colorectal cancer using CRISPR-Cas9-mediated engineering of human intestinal organoids

Mami Matano et al.

NATURE MEDICINE (2015)

Article Multidisciplinary Sciences

Preserved genetic diversity in organoids cultured from biopsies of human colorectal cancer metastases

Fleur Weeber et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Article Biochemistry & Molecular Biology

Identification of Multipotent Luminal Progenitor Cells in Human Prostate Organoid Cultures

Wouter R. Karthaus et al.

Article Biochemistry & Molecular Biology

Hippo Pathway Activity Influences Liver Cell Fate

Dean Yimlamai et al.

Article Cell Biology

Organoid cultures for the analysis of cancer phenotypes

Norman Sachs et al.

CURRENT OPINION IN GENETICS & DEVELOPMENT (2014)

Article Biotechnology & Applied Microbiology

Clinical development success rates for investigational drugs

Michael Hay et al.

NATURE BIOTECHNOLOGY (2014)

Article Biochemical Research Methods

Niche-independent high-purity cultures of Lgr5(+) intestinal stem cells and their progeny

Xiaolei Yin et al.

NATURE METHODS (2014)

Article Gastroenterology & Hepatology

Pancreatic cancer organotypics: High throughput, preclinical models for pharmacological agent evaluation

Stacey J. Coleman et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2014)

Article Biochemistry & Molecular Biology

Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis

Meritxell Huch et al.

EMBO JOURNAL (2013)

Review Oncology

Diagnostic, prognostic, and predictive biomarkers in pancreatic cancer

Jordan M. Winter et al.

JOURNAL OF SURGICAL ONCOLOGY (2013)

Article Multidisciplinary Sciences

In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration

Meritxell Huch et al.

NATURE (2013)

Article Biochemical Research Methods

In vitro expansion and genetic modification of gastrointestinal stem cells in spheroid culture

Hiroyuki Miyoshi et al.

NATURE PROTOCOLS (2013)

Article Multidisciplinary Sciences

Genetic reconstitution of tumorigenesis in primary intestinal cells

Kunishige Onuma et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Multidisciplinary Sciences

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

Andrew V. Biankin et al.

NATURE (2012)

Review Oncology

Evolutionary dynamics of carcinogenesis and why targeted therapy does not work

Robert J. Gillies et al.

NATURE REVIEWS CANCER (2012)

Review Biochemistry & Molecular Biology

Hallmarks of Cancer: The Next Generation

Douglas Hanahan et al.

Review Gastroenterology & Hepatology

Leucine-Rich Repeat-Containing G-Protein-Coupled Receptors as Markers of Adult Stem Cells

Nick Barker et al.

GASTROENTEROLOGY (2010)

Review Medicine, General & Internal

Molecular Origins of Cancer: Molecular Basis of Colorectal Cancer.

Sanford D. Markowitz et al.

NEW ENGLAND JOURNAL OF MEDICINE (2009)

Article Gastroenterology & Hepatology

1423 pancreaticoduodenectomies for pancreatic cancer: A single-institution experience

Jordan M. Winter et al.

JOURNAL OF GASTROINTESTINAL SURGERY (2006)

Review Medicine, General & Internal

Pancreatic cancer

DH Li et al.

LANCET (2004)