Journal
BRAIN TUMOR PATHOLOGY
Volume 35, Issue 2, Pages 62-70Publisher
SPRINGER JAPAN KK
DOI: 10.1007/s10014-018-0311-6
Keywords
WHO classification of endocrine tumors; Posterior pituitary tumor; Pituicytoma; Granular cell tumor; Spindle cell oncocytoma
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The fourth edition of the World Health Organization classification of endocrine tumors (EN-WHO2017) was released in 2017. In this new edition, changes in the classification of non-neuroendocrine tumors are proposed particularly in tumors arising in the posterior pituitary. These tumors are a distinct group of low-grade neoplasms of the sellar region that express thyroid transcription factor-1, and include pituicytoma, granular cell tumor of the sellar region, spindle cell oncocytoma, and sellar ependymoma. This short review focuses on the classification of posterior pituitary tumors newly proposed in EN-WHO2017, and controversies in their pathological differential diagnosis are discussed based on recent cases.
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