Journal
WORLD JOURNAL OF ORTHOPEDICS
Volume 7, Issue 1, Pages 20-29Publisher
BAISHIDENG PUBLISHING GROUP INC
DOI: 10.5312/wjo.v7.i1.20
Keywords
Cervical myelopathy; Cervical spine; Neck pain
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Cervical myelopathy is a well-described clinical syndrome that may evolve from a combination of etiological mechanisms. It is traditionally classified by cervical spinal cord and/or nerve root compression which varies in severity and number of levels involved. The vast array of clinical manifestations of cervical myelopathy cannot fully be explained by the simple concept that a narrowed spinal canal causes compression of the cord, local tissue ischemia, injury and neurological impairment. Despite advances in surgical technology and treatment innovations, there are limited neuro-protective treatments for cervical myelopathy, which reflects an incomplete understanding of the patho-physiological processes involved in this disease. The aim of this review is to provide a comprehensive overview of the key pathophysiological processes at play in the development of cervical myelopathy.
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