4.8 Article

Measuring and mapping the global burden of antimicrobial resistance

Journal

BMC MEDICINE
Volume 16, Issue -, Pages -

Publisher

BMC
DOI: 10.1186/s12916-018-1073-z

Keywords

Antimicrobial resistance; Drug-resistant infections; Microbial; Anti-infective agents; Antimicrobial drugs; Global health; Global burden of disease; Public health

Funding

  1. United Kingdom's Department of Health and Social Care, Fleming Fund
  2. Wellcome Trust [209142/Z/17/Z]
  3. Bill and Melinda Gates Foundation [OPP1176062]
  4. Bill and Melinda Gates Foundation [OPP1176062] Funding Source: Bill and Melinda Gates Foundation
  5. Wellcome Trust [209142/Z/17/Z] Funding Source: Wellcome Trust

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The increasing number and global distribution of pathogens resistant to antimicrobial drugs is potentially one of the greatest threats to global health, leading to health crises arising from infections that were once easy to treat. Infections resistant to antimicrobial treatment frequently result in longer hospital stays, higher medical costs, and increased mortality. Despite the long-standing recognition of antimicrobial resistance (AMR) across many settings, there is surprisingly poor information about its geographical distribution over time and trends in its population prevalence and incidence. This makes reliable assessments of the health burden attributable to AMR difficult, weakening the evidence base to drive forward research and policy agendas to combat AMR. The inclusion of mortality and morbidity data related to drug-resistant infections into the annual Global Burden of Disease Study should help fill this policy void.

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