4.6 Article

Enhanced JBrowse plugins for epigenomics data visualization

Journal

BMC BIOINFORMATICS
Volume 19, Issue -, Pages -

Publisher

BMC
DOI: 10.1186/s12859-018-2160-z

Keywords

Epigenomics; Genomics; Genome browser; Visualization

Funding

  1. National Institute of General Medical Sciences of the National Institutes of Health [T32GM007103]
  2. National Science Foundation [IOS-1546867]
  3. Office of Research at the University of Georgia

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Background: New sequencing techniques require new visualization strategies, as is the case for epigenomics data such as DNA base modifications, small non-coding RNAs, and histone modifications. Results: We present a set of plugins for the genome browser JBrowse that are targeted for epigenomics visualizations. Specifically, we have focused on visualizing DNA base modifications, small non-coding RNAs, stranded read coverage, and sequence motif density. Additionally, we present several plugins for improved user experience such as configurable, high-quality screenshots. Conclusions: In visualizing epigenomics with traditional genomics data, we see these plugins improving scientific communication and leading to discoveries within the field of epigenomics.

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