Journal
AUSTRALIAN PRESCRIBER
Volume 39, Issue 1, Pages 21-24Publisher
NATL PRESCRIBING SERVICE LTD
DOI: 10.18773/austprescr.2016.008
Keywords
haemodialysis; kidney; pharmacokinetics; renal disease
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The pharmacokinetics of a drug may be altered in patients with renal impairment who require dialysis. Some drugs are contraindicated. The drug's clearance and therapeutic index determine if a dose adjustment is needed. A lower dose or less frequent dosing may be required. Consult a reference source or the patient's nephrologist before prescribing. Start at a low dose and increase gradually. If possible give once-daily drugs after dialysis.
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