Journal
CLINICS IN ORTHOPEDIC SURGERY
Volume 8, Issue 1, Pages 1-8Publisher
KOREAN ORTHOPAEDIC ASSOC
DOI: 10.4055/cios.2016.8.1.1
Keywords
Hip; Osteonecrosis; Cell therapy; Mesenchymal stromal cells; Tissue engineering
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Avascular necrosis of the femoral head is caused by a multitude of etiologic factors and is associated with collapse with a risk of hip arthroplasty in younger populations. A focus on early disease management with the use of stem cells was proposed as early as 1985 by the senior author (PH). We undertook a systematic review of the medical literature to examine the progress in cell therapy during the last 30 years for the treatment of early stage osteonecrosis.
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