Journal
DATA IN BRIEF
Volume 6, Issue -, Pages 1023-1027Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.dib.2016.02.004
Keywords
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Categories
Funding
- FCT, the Portuguese Foundation for Science and Technology
- FEDER funds through the Operational Programme for Competitiveness Factors-COMPETE - Programa Operacional Regional do Norte (ON.2 - O Novo Norte), through the Quadro de Referencia Estrategico Nacional (QREN)
- FCT-Foundation for Science and Technology - Programa Operacional Regional do Norte (ON.2 - O Novo Norte), through FEDER funds under the Quadro de Referencia Estrategico Nacional (QREN) [PEst-C/SAU/LA0003/2013, NORTE-07-0162-FEDER-00018, NORTE-07-0162-FEDER-000067]
- Science Foundation Ireland [08/SRC/B1410]
- Irish Cancer Society [CCRC13GAL]
- Portuguese Foundation for Science and Technology (FCT) [SFRH/BD/87646/2012, SFRH/BD/98054/2013, SFRH/BPD/68787/2010]
- Fundação para a Ciência e a Tecnologia [SFRH/BD/87646/2012, SFRH/BD/98054/2013] Funding Source: FCT
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To date, there are no simple and minimally invasive methods to diagnose MDR. Extracellular vesicles (EVs) are shed by all cells, carry a specific cargo from the donor cells and are present in several body fluids, which means that they can potentially be easily collected from cancer patients and become the source of biomarkers to diagnose cancer. This data article contains a full list of the proteins identified in the EVs shed by an isogenic pair of chronic myeloid leukaemia cells (MDR cells and their drug-sensitive counterparts) by LC/MS/MS analysis, together with their GeneOntology analysis. In addition, it also contains data from protein content analysis and Dynamic light scattering count-rate events of the referred EVs as well as of the EVs shed from an isogenic pair of non-small cell lung cancer cells (MDR cells and their drug-sensitive counterparts). The interpretation of the data presented in this article and further extensive insights can be found in Multidrug resistant tumour cells shed more microvesicles-like EVs and less exosomes than their drug-sensitive counterpart cells [1]. (C) 2016 The Authors. Published by Elsevier Inc. This is an open access article under the CCBY license (http://creativecommons.org/licenses/by/4.0/).
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