Journal
JOURNAL OF THE EGYPTIAN NATIONAL CANCER INSTITUTE
Volume 28, Issue 1, Pages 7-11Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jnci.2015.08.001
Keywords
Radiation induced liver disease; Patho-physiology; Risk factors; Management
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Radiation-induced liver disease (RILD) or radiation hepatitis is a sub-acute form of liver injury due to radiation. It is one of the most dreaded complications of radiation which prevents radiation dose escalation and re-irradiation for hepatobiliary or upper gastrointestinal malignancies. This complication should be kept in mind whenever a patient is planned for irradiation of these malignancies. Although, incidence of RILD is decreasing due to better knowledge of liver tolerance, improved investigation modalities and modern radiation delivery techniques, treatment options are still limited. In this review article, we have focussed on patho-physiology, risk factors, prevention and management of RILD. (C) 2015 The Authors. Production and hosting by Elsevier B. V. on behalf of National Cancer Institute, Cairo University.
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