Journal
BIOLOGICAL CHEMISTRY
Volume 399, Issue 7, Pages 799-808Publisher
WALTER DE GRUYTER GMBH
DOI: 10.1515/hsz-2018-0157
Keywords
archaellum; cryoEM; flagellum; structure; twitching motility; type IV pili
Categories
Funding
- University of Exeter
- BBSRC [BB/R008639/1] Funding Source: UKRI
Ask authors/readers for more resources
Bacteria and archaea are evolutionarily distinct prokaryotes that diverged from a common ancestor billions of years ago. However, both bacteria and archaea assemble long, helical protein filaments on their surface through a machinery that is conserved at its core. In both domains of life, the filaments are required for a diverse array of important cellular processes including cell motility, adhesion, communication and biofilm formation. In this review, we highlight the recent structures of both the type IV pilus machinery and the archaellum determined in situ. We describe the current level of functional understanding and discuss how this relates to the pressures facing bacteria and archaea throughout evolution.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available