Journal
BIOINFORMATICS
Volume 34, Issue 21, Pages 3771-3772Publisher
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/bty411
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Funding
- National Key Research and Development Program of China [2017YFA0700403]
- National Natural Science Foundation of China [31471247, 31771458]
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The availability of cancer genomic data makes it possible to analyze genes related to cancer. Cancer is usually the result of a set of genes and the signal of a single gene could be covered by background noise. Here, we present a web server named Gene Set Cancer Analysis (GSCALite) to analyze a set of genes in cancers with the following functional modules. (i) Differential expression in tumor versus normal, and the survival analysis; (ii) Genomic variations and their survival analysis; (iii) Gene expression associated cancer pathway activity; (iv) miRNA regulatory network for genes; (v) Drug sensitivity for genes; (vi) Normal tissue expression and eQTL for genes. GSCALite is a user-friendly web server for dynamic analysis and visualization of gene set in cancer and drug sensitivity correlation, which will be of broad utilities to cancer researchers.
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