4.7 Article

Cluster Locator, online analysis and visualization of gene clustering

Journal

BIOINFORMATICS
Volume 34, Issue 19, Pages 3377-3379

Publisher

OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/bty336

Keywords

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Funding

  1. National Agency of Research and Innovation (ANII)
  2. Program for the Development of Basic Sciences (PEDECIBA)
  3. Basque Department of Industry, Tourism and Trade (Etortek Program)
  4. Basque Department of Industry, Tourism and Trade (Elkartek Program)
  5. Innovation Technology Department of Bizkaia County
  6. CIBERehd Network
  7. Spanish MINECO [BFU2014-52282-P, BFU2017-84653-P]
  8. Severo Ochoa Excellence Accreditation [SEV-2016-0644]

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Genes sharing functions, expression patterns or quantitative traits are not randomly distributed along eukaryotic genomes. In order to study the distribution of genes that share a given feature, we present Cluster Locator, an online analysis and visualization tool. Cluster Locator determines the number, size and position of all the clusters formed by the protein-coding genes on a list according to a given maximum gap, the percentage of gene clustering of the list and its statistical significance. The output includes a visual representation of the distribution of genes and gene clusters along the reference genome. Availability and implementation: Cluster Locator is freely available at http://clusterlocator.bnd.edu.uy/.

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