Journal
BIOCHEMICAL SOCIETY TRANSACTIONS
Volume 46, Issue -, Pages 587-597Publisher
PORTLAND PRESS LTD
DOI: 10.1042/BST20160144
Keywords
-
Categories
Funding
- National Institute of Health [GM19301, GM100310]
Ask authors/readers for more resources
Allostery is a fundamental regulatory mechanism in biology. Although generally accepted that it is a dynamics-driven process, the exact molecular mechanism of allosteric signal transmission is hotly debated. We argue that allostery is as a part of a bigger picture that also includes fractal-like properties of protein interior, hierarchical protein folding and entropy-driven molecular recognition. Although so far all these phenomena were studied separately, they stem from the same common root: self-organization of polypeptide chains and, thus, has to be studied collectively. This merge will allow the cross-referencing of a broad spectrum of multi-disciplinary data facilitating progress in all these fields.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available