Journal
CURRENT OPINION IN BEHAVIORAL SCIENCES
Volume 8, Issue -, Pages 53-59Publisher
ELSEVIER
DOI: 10.1016/j.cobeha.2016.01.013
Keywords
-
Funding
- US National Institutes of Health [R01 MH093727]
- Swedish Research Council [349-2007-8695, 09899]
Ask authors/readers for more resources
In classical eyeblink conditioning a subject learns to blink to a previously neutral stimulus. This conditional response is timed to occur just before an air puff to the eye. The learning is known to depend on the cerebellar cortex where Purkinje cells respond with adaptively timed pauses in their spontaneous firing. The pauses in the inhibitory Purkinje cells cause disinhibition of the cerebellar nuclei, which elicit the overt blinks. The timing of a Purkinje cell response was previously thought to require a temporal code in the input signal but recent work suggests that the Purkinje cells can learn to time their responses through an intrinsic mechanism that is activated by metabotropic glutamate receptors (mGluR7).
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available