Journal
BEST PRACTICE & RESEARCH-CLINICAL ANAESTHESIOLOGY
Volume 30, Issue 1, Pages 79-89Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.bpa.2015.11.002
Keywords
dexmedetomidine; gabapentin; ketamine; multimodal pain management; paracetamol; perioperative pain; postoperative pain; pregabalin
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Perioperative pain management is a significant challenge following major spine surgery. Many pathways contribute to perioperative pain, including nociceptive, inflammatory, and neuropathic sources. Although opioids have long been a mainstay for perioperative analgesia, other non-opioid therapies have been increasingly used as part of a multimodal analgesic regimen to provide improved pain control while minimizing opioid-related side effects. Here we review the evidence supporting the use of novel analgesic approaches as an alternative to intravenous opioids for major spine surgery. (C) 2015 Elsevier Ltd. All rights reserved.
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