Journal
FUTURE JOURNAL OF PHARMACEUTICAL SCIENCES
Volume 2, Issue 1, Pages 9-19Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.fjps.2016.02.001
Keywords
Quinazolines; EGFR inhibitors; Protein kinases; Tyrosine kinase inhibitors
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Quinazoline derivatives are fused heterocyclic ring systems which have been explored for their inhibitory activity towards various protein kinase enzymes and their role as anticancer agents. The present review to represent the most recent synthetic strategies and medicinal aspects including structure activity relationships of substituted quinazolines as EGFR inhibitors reported to date. (C) 2016 Future University. Production and hosting by Elsevier B.V.
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