4.1 Review

Regulation of Escherichia coli Biofilm Formation

Journal

APPLIED BIOCHEMISTRY AND MICROBIOLOGY
Volume 54, Issue 1, Pages 1-11

Publisher

PLEIADES PUBLISHING INC
DOI: 10.1134/S0003683818010040

Keywords

biofilm; cAMP; c-di-GMP; sigma-factor; sRNA; two-component system; quorum sensing

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The review considers the regulatory mechanisms controlling the formation of biofilms by bacteria Escherichia coli. Under harsh conditions, microbial populations transfer to the structured mode of existence by building biofilms. The regulation of biofilm formation is a complex multistage process. Environmental signals are perceived by two-component signaling systems, which fulfill their transduction to the genome. This switches microbial cells from the planktonic motile lifestyle to the sessile.

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