Journal
ANNUAL REVIEW OF ANALYTICAL CHEMISTRY, VOL 11
Volume 11, Issue -, Pages 101-126Publisher
ANNUAL REVIEWS
DOI: 10.1146/annurev-anchem-061417-125705
Keywords
vertical structures; biointerface; electrophysiology; molecular delivery; electron microscopy
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Funding
- NIGMS NIH HHS [R01 GM125737] Funding Source: Medline
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Measurements of the intracellular state of mammalian cells often require probes or molecules to breach the tightly regulated cell membrane. Mammalian cells have been shown to grow well on vertical nanoscale structures in vitro, going out of their way to reach and tightly wrap the structures. A great deal of research has taken advantage of this interaction to bring probes close to the interface or deliver molecules with increased efficiency or ease. In turn, techniques have been developed to characterize this interface. Here, we endeavor to survey this research with an emphasis on the interface as driven by cellular mechanisms.
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