4.5 Review

Are big potassium-type Ca2+-activated potassium channels a viable target for the treatment of epilepsy?

Related references

Note: Only part of the references are listed.
Article Clinical Neurology

Cyclooxygenase-2 in epilepsy

Asheebo Rojas et al.

EPILEPSIA (2014)

Review Behavioral Sciences

Cannabis, cannabidiol, and epilepsy - From receptors to clinical response

Jerzy P. Szaflarski et al.

EPILEPSY & BEHAVIOR (2014)

Article Neurosciences

Mechanism of the medium-duration afterhyperpolarization in rat serotonergic neurons

Philippe Alix et al.

EUROPEAN JOURNAL OF NEUROSCIENCE (2014)

Article Biochemistry & Molecular Biology

Structural Basis for Calcium and Magnesium Regulation of a Large Conductance Calcium-activated Potassium Channel with β1 Subunits

Hao-Wen Liu et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2014)

Review Clinical Neurology

Anti-epileptogenic Clinical Trial Designs in Epilepsy: Issues and Options

Dieter Schmidt et al.

NEUROTHERAPEUTICS (2014)

Editorial Material Clinical Neurology

Novel Concepts in Epileptogenesis and its Prevention

Lara E. Jehi et al.

NEUROTHERAPEUTICS (2014)

Article Multidisciplinary Sciences

Intrinsic Disorder in the BK Channel and Its Interactome

Zhenling Peng et al.

PLOS ONE (2014)

Review Physiology

MaxiK channel and cell signalling

Ligia Toro et al.

PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2014)

Review Pharmacology & Pharmacy

Antiarrhythmic drugs and epilepsy

Kinga K. Borowicz et al.

PHARMACOLOGICAL REPORTS (2014)

Review Pharmacology & Pharmacy

Palmitoylethanolamide in CNS health and disease

Giuseppina Mattace Raso et al.

PHARMACOLOGICAL RESEARCH (2014)

Review Physiology

BK channel activators and their therapeutic perspectives

Bo H. Bentzen et al.

FRONTIERS IN PHYSIOLOGY (2014)

Article Biochemistry & Molecular Biology

Regulation of large conductance calcium- and voltage-activated potassium (BK) channels by S-palmitoylation

Michael J. Shipston

BIOCHEMICAL SOCIETY TRANSACTIONS (2013)

Article Clinical Neurology

Kv7 potassium channel activation with ICA-105665 reduces photoparoxysmal EEG responses in patients with epilepsy

Dorothee G. A. Kasteleijn-Nolst Trenite et al.

EPILEPSIA (2013)

Article Clinical Neurology

Development of new treatment approaches for epilepsy: Unmet needs and opportunities

Jacqueline A. French et al.

EPILEPSIA (2013)

Article Behavioral Sciences

Adjunctive use of verapamil in patients with refractory temporal lobe epilepsy: A pilot study

Ali A. Asadi-Pooya et al.

EPILEPSY & BEHAVIOR (2013)

Article Physiology

Interaction between residues in the Mg2+-binding site regulates BK channel activation

Junqiu Yang et al.

JOURNAL OF GENERAL PHYSIOLOGY (2013)

Review Neurosciences

The role of inflammation in epileptogenesis

Annamaria Vezzani et al.

NEUROPHARMACOLOGY (2013)

Article Physiology

Ca2+-dependent large conductance K+ currents in thalamocortical relay neurons of different rat strains

Petra Ehling et al.

PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2013)

Article Multidisciplinary Sciences

Mechanism of the modulation of BK potassium channel complexes with different auxiliary subunit compositions by the omega-3 fatty acid DHA

Toshinori Hoshi et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Review Neurosciences

Role of hormones and neurosteroids in epileptogenesis

Doodipala Samba Reddy

FRONTIERS IN CELLULAR NEUROSCIENCE (2013)

Review Neurosciences

Intracellular BKCa (iBKCa) channels

Harpreet Singh et al.

JOURNAL OF PHYSIOLOGY-LONDON (2012)

Review Pharmacology & Pharmacy

Large conductance, calcium- and voltage-gated potassium (BK) channels: Regulation by cholesterol

Alejandro M. Dopico et al.

PHARMACOLOGY & THERAPEUTICS (2012)

Article Multidisciplinary Sciences

Modulation of BK channel voltage gating by different auxiliary β subunits

Gustavo F. Contreras et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Multidisciplinary Sciences

BK potassium channel modulation by leucine-rich repeat-containing proteins

Jiusheng Yan et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Biochemistry & Molecular Biology

Electro-pharmacological profile of a mitochondrial inner membrane big-potassium channel from rat brain

J. Fahanik-babaei et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2011)

Review Pharmacology & Pharmacy

Targeting BK (big potassium) channels in epilepsy

Prosper N'Gouemo

EXPERT OPINION ON THERAPEUTIC TARGETS (2011)

Review Clinical Neurology

Mechanisms of epileptogenesis and potential treatment targets

Asla Pitkanen et al.

LANCET NEUROLOGY (2011)

Article Multidisciplinary Sciences

Unconventional myristoylation of large-conductance Ca2+-activated K+ channel (Slo1) via serine/threonine residues regulates channel surface expression

Abderrahmane Alioua et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Multidisciplinary Sciences

Alternatively spliced domains interact to regulate BK potassium channel gating

Brandon E. Johnson et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Biochemistry & Molecular Biology

Identification of a Thiol/Disulfide Redox Switch in the Human BK Channel That Controls Its Affinity for Heme and CO

Li Yi et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Biochemistry & Molecular Biology

Pre-synaptic BK channels selectively control glutamate versus GABA release from cortical and hippocampal nerve terminals

Maria Martire et al.

JOURNAL OF NEUROCHEMISTRY (2010)

Article Multidisciplinary Sciences

Structure of the Human BK Channel Ca2+-Activation Apparatus at 3.0 Å Resolution

Peng Yuan et al.

SCIENCE (2010)

Review Neurosciences

BK channel activation: structural and functional insights

Urvi S. Lee et al.

TRENDS IN NEUROSCIENCES (2010)

Review Biochemistry & Molecular Biology

Molecular mechanisms of BK channel activation

J. Cui et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2009)

Article Clinical Neurology

Anticonvulsant effects of the BK-channel antagonist paxilline

Jesse J. Sheehan et al.

EPILEPSIA (2009)

Article Physiology

Mechanism of Increased BK Channel Activation from a Channel Mutation that Causes Epilepsy

Bin Wang et al.

JOURNAL OF GENERAL PHYSIOLOGY (2009)

Article Neurosciences

Blocking the BK channel impedes acquisition of trace eyeblink conditioning

Elizabeth A. Matthews et al.

LEARNING & MEMORY (2009)

Article Neurosciences

Down-regulation of BK channel expression in the pilocarpine model of temporal lobe epilepsy

Luis F. Pacheco Otalora et al.

BRAIN RESEARCH (2008)

Review Biochemistry & Molecular Biology

BK channel modulators: A comprehensive overview

Antonio Nardi et al.

CURRENT MEDICINAL CHEMISTRY (2008)

Article Pharmacology & Pharmacy

K+-Channel Openers Suppress Epileptiform Activities Induced by 4-Aminopyridine in Cultured Rat Hippocampal Neurons

Kiyoaki Kobayashi et al.

JOURNAL OF PHARMACOLOGICAL SCIENCES (2008)

Article Biochemistry & Molecular Biology

Activation of Slo1 BK channels by Mg2+ coordinated between the voltage sensor and RCK1 domains

Huanghe Yang et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2008)

Article Neurosciences

Deficit of Kcnmal mRNA expression in the dentate gyrus of epileptic rats

Boris Ermolinsky et al.

NEUROREPORT (2008)

Article Genetics & Heredity

Allelic association of a truncation mutation of the KCNMB3 gene with idiopathic generalized epilepsy

Susanne Lorenz et al.

AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS (2007)

Review Neurosciences

High-conductance potassium channels of the SLO family

Lawrence Salkoff et al.

NATURE REVIEWS NEUROSCIENCE (2006)

Article Pharmacology & Pharmacy

Rapid broad-spectrum analgesia through activation of peroxisome proliferator-activated receptor-α

Jesse LoVerme et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2006)

Article Multidisciplinary Sciences

BKCa-Cav channel complexes mediate rapid and localized Ca2+-activated K+ signaling

Henrike Berkefeld et al.

SCIENCE (2006)

Article Physiology

Mechanism of β4 subunit modulation of BK channels

B Wang et al.

JOURNAL OF GENERAL PHYSIOLOGY (2006)

Article Medicine, Research & Experimental

Possible role of potassium channel, big K in etiology of Schizophrenia

Lei Zhang et al.

MEDICAL HYPOTHESES (2006)

Review Chemistry, Medicinal

Eburnamine derivatives and the brain

A Vas et al.

MEDICINAL RESEARCH REVIEWS (2005)

Article Chemistry, Medicinal

Compounds structurally related to tamoxifen as openers of large-conductance calcium-activated K+ channel

Y Sha et al.

CHEMICAL & PHARMACEUTICAL BULLETIN (2005)

Article Pharmacology & Pharmacy

Effect of MX-68 on airway inflammation and hyperresponsiveness in mice and guinea-pigs

K Nagao et al.

JOURNAL OF PHARMACY AND PHARMACOLOGY (2004)

Article Pharmacology & Pharmacy

Topiramate hyperpolarizes and modulates the slow poststimulus AHP of rat olfactory cortical neurones in vitro

E Russo et al.

BRITISH JOURNAL OF PHARMACOLOGY (2004)

Article Neurosciences

BK potassium channels control transmitter release at CA3-CA3 synapses in the rat hippocampus

G Raffaelli et al.

JOURNAL OF PHYSIOLOGY-LONDON (2004)

Review Neurosciences

Potassium channels as anti-epileptic drug targets

AD Wickenden

NEUROPHARMACOLOGY (2002)

Article Cell Biology

Modulation of BKCa channel activity by fatty acids:: structural requirements and mechanism of action

AL Clarke et al.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2002)

Article Multidisciplinary Sciences

Mechanism of magnesium activation of calcium-activated potassium channels

JY Shi et al.

NATURE (2002)

Article Multidisciplinary Sciences

Crystal structure and mechanism of a calcium-gated potassium channel

YX Jiang et al.

NATURE (2002)

Article Pharmacology & Pharmacy

Vinpocetine-induced stimulation of calcium-activated potassium currents in rat pituitary GH3 cells

SN Wu et al.

BIOCHEMICAL PHARMACOLOGY (2001)

Article Pharmacology & Pharmacy

Pharmacokinetics of andolast after administration of single escalating doses by inhalation in mild asthmatic patients

S Persiani et al.

BIOPHARMACEUTICS & DRUG DISPOSITION (2001)

Article Biochemistry & Molecular Biology

Verapamil block of large-conductance Ca-activated K channels in rat aortic myocytes

AA Harper et al.

JOURNAL OF MEMBRANE BIOLOGY (2001)

Article Pharmacology & Pharmacy

NMDA and AMPA/kainate receptors are involved in the anticonvulsant activity of riluzole in DBA/2 mice

G De Sarro et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2000)

Article Multidisciplinary Sciences

A neuronal β subunit (KCNMB4) makes the large conductance, voltage- and Ca2+-activated K+ channel resistant to chavybdotoxin and iberiotoxin

P Meera et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)