Related references
Note: Only part of the references are listed.Apc Restoration Promotes Cellular Differentiation and Reestablishes Crypt Homeostasis in Colorectal Cancer
Lukas E. Dow et al.
CELL (2015)
Japanese Society for Cancer of the Colon and Rectum (JSCCR) Guidelines 2014 for treatment of colorectal cancer
Toshiaki Watanabe et al.
INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY (2015)
Targeting the Wnt pathway in human cancers: Therapeutic targeting with a focus on OMP-54F28
Phuong N. Le et al.
PHARMACOLOGY & THERAPEUTICS (2015)
Suppression of cancer relapse and metastasis by inhibiting cancer stemness
Youzhi Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Safely targeting cancer stem cells via selective catenin coactivator antagonism
Heinz-Josef Lenz et al.
CANCER SCIENCE (2014)
Stem Cells Marked by the R-Spondin Receptor LGR5
Bon-Kyoung Koo et al.
GASTROENTEROLOGY (2014)
Meat Consumption and Colorectal Cancer Risk: An Evaluation Based on a Systematic Review of Epidemiologic Evidence Among the Japanese Population
Ngoc Minh Pham et al.
JAPANESE JOURNAL OF CLINICAL ONCOLOGY (2014)
Can we safely target the WNT pathway?
Michael Kahn
NATURE REVIEWS DRUG DISCOVERY (2014)
A Novel Aminothiazole KY-05009 with Potential to Inhibit Traf2-and Nck-Interacting Kinase (TNIK) Attenuates TGF-β1-Mediated Epithelial-to-Mesenchymal Transition in Human Lung Adenocarcinoma A549 Cells
Jiyeon Kim et al.
PLOS ONE (2014)
The essential role of TNIK gene amplification in gastric cancer growth
D-H Yu et al.
ONCOGENESIS (2014)
Discovery of 4-phenyl-2-phenylaminopyridine based TNIK inhibitors
Koc-Kan Ho et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2013)
Gene rearrangements in hormone receptor negative breast cancers revealed by mate pair sequencing
Xiang Jiao et al.
BMC GENOMICS (2013)
Targeting Wnt signaling: Discovery and characterization of novel thiazole-based Traf2-and NCK-interacting kinase (TNIK) inhibitors
Yuko Uno et al.
MOLECULAR CANCER THERAPEUTICS (2013)
Regorafenib monotherapy for previously treated metastatic colorectal cancer (CORRECT): an international, multicentre, randomised, placebo-controlled, phase 3 trial
Axel Grothey et al.
LANCET (2013)
Active site profiling reveals coupling between domains in SRC-family kinases
Ratika Krishnamurty et al.
NATURE CHEMICAL BIOLOGY (2013)
Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974
Jun Liu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
TGF-β signalling and its role in cancer progression and metastasis
Yvette Drabsch et al.
CANCER AND METASTASIS REVIEWS (2012)
A Novel Tankyrase Inhibitor Decreases Canonical Wnt Signaling in Colon Carcinoma Cells and Reduces Tumor Growth in Conditional APC Mutant Mice
Jo Waaler et al.
CANCER RESEARCH (2012)
Wnt/β-Catenin Signaling and Disease
Hans Clevers et al.
CELL (2012)
TNiK Is Required for Postsynaptic and Nuclear Signaling Pathways and Cognitive Function
Marcelo P. Coba et al.
JOURNAL OF NEUROSCIENCE (2012)
A Critical Role for the Wnt Effector Tcf4 in Adult Intestinal Homeostatic Self-Renewal
Johan H. van Es et al.
MOLECULAR AND CELLULAR BIOLOGY (2012)
Comprehensive molecular characterization of human colon and rectal cancer
Donna M. Muzny et al.
NATURE (2012)
Multifunctional roles of gelsolin in health and diseases
Guo Hua Li et al.
MEDICINAL RESEARCH REVIEWS (2012)
Wnt pathway inhibition via the targeting of Frizzled receptors results in decreased growth and tumorigenicity of human tumors
Austin Gurney et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Activation of canonical Wnt signalling is required for TGF-β-mediated fibrosis
Alfiya Akhmetshina et al.
NATURE COMMUNICATIONS (2012)
The Germinal Center Kinase TNIK Is Required for Canonical NF-κB and JNK Signaling in B-Cells by the EBV Oncoprotein LMP1 and the CD40 Receptor
Anna Shkoda et al.
PLOS BIOLOGY (2012)
STAT3 Is Necessary for Proliferation and Survival in Colon Cancer-Initiating Cells
Li Lin et al.
CANCER RESEARCH (2011)
Targeted Therapy in Colorectal Cancer: Current Status and Future Challenges
A. K. Koutras et al.
CURRENT MEDICINAL CHEMISTRY (2011)
The enormous influence of TNIK knockdown on intracellular signals and cell survival
Jinghua Gui et al.
HUMAN CELL (2011)
Traf2-and Nck-Interacting Kinase Is Essential for Wnt Signaling and Colorectal Cancer Growth
Miki Shitashige et al.
CANCER RESEARCH (2010)
Transcriptional crosstalk between TGFβ and stem cell pathways in tumor cell invasion Role of EMT promoting Smad complexes
Jonas Fuxe et al.
CELL CYCLE (2010)
Traf2-and Nck-interacting Kinase Is Essential for Canonical Wnt Signaling in Xenopus Axis Formation
Reiko Satow et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Epithelial-Mesenchymal Transitions in Development and Disease
Jean Paul Thiery et al.
CELL (2009)
The kinase TNIK is an essential activator of Wnt target genes
Tokameh Mahmoudi et al.
EMBO JOURNAL (2009)
The basics of epithelial-mesenchymal transition
Raghu Kalluri et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
Crypt stem cells as the cells-of-origin of intestinal cancer
Nick Barker et al.
NATURE (2009)
Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling
Shih-Min A. Huang et al.
NATURE (2009)
Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer
Baozhi Chen et al.
NATURE CHEMICAL BIOLOGY (2009)
Advances in chemotherapy against advanced or metastatic colorectal cancer
Kenji Omura
DIGESTION (2008)
Regulation of Wnt signaling by the nuclear pore complex
Miki Shitashige et al.
GASTROENTEROLOGY (2008)
The genomic landscapes of human breast and colorectal cancers
Laura D. Wood et al.
SCIENCE (2007)
CBP/p300 are bimodal regulators of Wnt signaling
Jiong Li et al.
EMBO JOURNAL (2007)
Myc deletion rescues Apc deficiency in the small intestine
Owen J. Sansom et al.
NATURE (2007)
Wnt/β-catenin signaling in cancer stemness and malignant behavior
Riccardo Fodde et al.
CURRENT OPINION IN CELL BIOLOGY (2007)
A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
Catherine A. O'Brien et al.
NATURE (2007)
Surgical treatment for digestive cancer
Kiyotaka Okuno
DIGESTIVE SURGERY (2007)
Physical activity and colorectal cancer: The Fukuoka colorectal cancer study
Kayoko Isomura et al.
CANCER SCIENCE (2006)
E-cadherin regulates the association between β-catenin and actinin-4
Y Hayashida et al.
CANCER RESEARCH (2005)
A small molecule inhibitor of β-catenin/cyclic AMP response element-binding protein transcription
KH Emami et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
The Traf2- and Nck-interacting kinase as a putative effector of Rap2 to regulate actin cytoskeleton
K Taira et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration
OJ Sansom et al.
GENES & DEVELOPMENT (2004)
Survivin and molecular pathogenesis of colorectal cancer
PJ Kim et al.
LANCET (2003)
Overexpression of orphan G-Protein-coupled receptor, Gpr49, in human hepatocellular carcinomas with β-catenin mutations
Y Yamamoto et al.
HEPATOLOGY (2003)