Related references
Note: Only part of the references are listed.X-ray Structures of Human Furin in Complex with Competitive Inhibitors
Sven O. Dahms et al.
ACS CHEMICAL BIOLOGY (2014)
Optimization of Furin Inhibitors To Protect against the Activation of Influenza Hemagglutinin H5 and Shiga Toxin
Hugo Gagnon et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
Design, Synthesis, and Structure-Activity Relationship Studies of a Potent PACE4 Inhibitor
Anna Kwiatkowska et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
The Future of Peptide-based Drugs
David J. Craik et al.
CHEMICAL BIOLOGY & DRUG DESIGN (2013)
A role for PACE4 in osteoarthritis pain: evidence from human genetic association and null mutant phenotype
Anne-Marie Malfait et al.
ANNALS OF THE RHEUMATIC DISEASES (2012)
Protective Role of Systemic Furin in Immune Response-Induced Arthritis
Hilene Lin et al.
ARTHRITIS AND RHEUMATISM (2012)
SKI-1 and Furin Generate Multiple RGMa Fragments that Regulate Axonal Growth
Nardos G. Tassew et al.
DEVELOPMENTAL CELL (2012)
Highly Potent Inhibitors of Proprotein Convertase Furin as Potential Drugs for Treatment of Infectious Diseases
Gero L. Becker et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
The Multi-Leu Peptide Inhibitor Discriminates Between PACE4 and Furin And Exhibits Antiproliferative Effects On Prostate Cancer Cells
Christine Levesque et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Phase I Trial of bi-shRNAifurin/GMCSF DNA/Autologous Tumor Cell Vaccine (FANG) in Advanced Cancer
Neil Senzer et al.
MOLECULAR THERAPY (2012)
The biology and therapeutic targeting of the proprotein convertases
Nabil G. Seidah et al.
NATURE REVIEWS DRUG DISCOVERY (2012)
Proteolytic processing of vascular endothelial growth factor-D is essential for its capacity to promote the growth and spread of cancer
Nicole C. Harris et al.
FASEB JOURNAL (2011)
MECHANISMS OF DISEASE Proprotein Convertases in Health and Disease
Andrew W. Artenstein et al.
NEW ENGLAND JOURNAL OF MEDICINE (2011)
Molecular Validation of PACE4 as a Target in Prostate Cancer
Francois D'Anjou et al.
TRANSLATIONAL ONCOLOGY (2011)
Partial maturation: an immune-evasion strategy of dengue virus?
Izabela A. Rodenhuis-Zybert et al.
TRENDS IN MICROBIOLOGY (2011)
Nona-D-Arginine Amide Suppresses Corneal Cytokines in Pseudomonas aeruginosa Keratitis
Priyanka Karicherla et al.
CORNEA (2010)
Nona-D-Arginine Amide for Prophylaxis and Treatment of Experimental Pseudomonas aeruginosa Keratitis
Priyanka Karicherla et al.
CURRENT EYE RESEARCH (2010)
Selective and potent furin inhibitors protect cells from anthrax without significant toxicity
Albert G. Remacle et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2010)
Potent Inhibitors of Furin and Furin-like Proprotein Convertases Containing Decarboxylated P1 Arginine Mimetics
Gero L. Becker et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
Proprotein Convertase Inhibition Results in Decreased Skin Cell Proliferation, Tumorigenesis, and Metastasis
Daniel E. Bassi et al.
NEOPLASIA (2010)
Anti-inflammatory and pro-inflammatory roles of TGF-β, IL-10, and IL-22 in immunity and autoimmunity
Shomyseh Sanjabi et al.
CURRENT OPINION IN PHARMACOLOGY (2009)
BRI3 Inhibits Amyloid Precursor Protein Processing in a Mechanistically Distinct Manner from Its Homologue Dementia Gene BRI2
Shuji Matsuda et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Nona-D-Arginine Therapy for Pseudomonas aeruginosa Keratitis
Priyanka Karicherla et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2009)
Knock-out mouse models of proprotein convertases: unique functions or redundancy?
John W. M. Creemers et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2008)
T-cell-expressed proprotein convertase furin is essential for maintenance of peripheral immune tolerance
Marko Pesu et al.
NATURE (2008)
Proprotein convertases promote processing of VEGF-D, a critical step for binding the angiogenic receptor VEGFR-2
Bradley K. McColl et al.
FASEB JOURNAL (2007)
Proprotein convertases:: lessons from knockouts
Nathalie Scamuffa et al.
FASEB JOURNAL (2006)
TGFβ:: the molecular Jekyll and Hyde of cancer
Brian Bierie et al.
NATURE REVIEWS CANCER (2006)
TGF-β directly targets cytotoxic T cell functions during tumor evasion of immune surveillance
DA Thomas et al.
CANCER CELL (2005)
Proprotein convertases: Master switches in the regulation of tumor growth and progression
DE Bassi et al.
MOLECULAR CARCINOGENESIS (2005)
Modulating furin activity with designed mini-PDX peptides: Synthesis and in vitro kinetic evaluation
A Basak et al.
FEBS LETTERS (2005)
Cutting back on pro-protein convertases:: the latest approaches to pharmacological inhibition
M Fugère et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2005)
Proprotein convertase models based on the crystal structures of furin and kexin: Explanation of their specificity
S Henrich et al.
JOURNAL OF MOLECULAR BIOLOGY (2005)
Role of interleukin-1 and tumor necrosis factor a in matrix degradation of human osteoarthritic cartilage
M Kobayashi et al.
ARTHRITIS AND RHEUMATISM (2005)
TGF-β signaling and the fibrotic response
A Leask et al.
FASEB JOURNAL (2004)
Pathway for polyarginine entry into mammalian cell
SM Fuchs et al.
BIOCHEMISTRY (2004)
Inhibition of furin by polyarginine-containing peptides - Nanomolar inhibition by NONA-D-arginine
MM Kacprzak et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Limited redundancy of the proprotein convertase furin in mouse liver
AJM Roebroek et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Polyarginine inhibits gp160 processing by furin and suppresses productive human immunodeficiency virus type 1 infection
KV Kibler et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Protection against anthrax toxemia by hexa-D-arginine in vitro and in vivo
MS Sarac et al.
INFECTION AND IMMUNITY (2004)
Curbing activation: proprotein convertases in homeostasis and pathology
NA Taylor et al.
FASEB JOURNAL (2003)
The crystal structure of the proprotein processing proteinase furin explains its stringent specificity
S Henrich et al.
NATURE STRUCTURAL BIOLOGY (2003)
Increased furin activity enhances the malignant phenotype of human head and neck cancer cells
DE Bassi et al.
AMERICAN JOURNAL OF PATHOLOGY (2003)
Human papillomavirus and cervical cancer
EM Burd
CLINICAL MICROBIOLOGY REVIEWS (2003)
The furin inhibitor hexa-D-arginine blocks the activation of Pseudomonas aeruginosa exotoxin A in vivo
MS Sarac et al.
INFECTION AND IMMUNITY (2002)
Furin at the cutting edge: From protein traffic to embryogenesis and disease
G Thomas
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2002)
Proprotein convertases in tumor progression and malignancy -: Novel targets in cancer therapy
AM Khatib et al.
AMERICAN JOURNAL OF PATHOLOGY (2002)
Inhibitory potency and specificity of subtilase-like pro-protein convertase (SPC) prodomains
M Fugère et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Reverse genetics demonstrates that proteolytic processing of the Ebola virus glycoprotein is not essential for replication in cell culture
G Neumann et al.
JOURNAL OF VIROLOGY (2002)
Enhancing the proteolytic maturation of human immunodeficiency virus type 1 envelope glycoproteins
JM Binley et al.
JOURNAL OF VIROLOGY (2002)
Elevated furin expression in aggressive human head and neck tumors and tumors cell lines
DE Bassi et al.
MOLECULAR CARCINOGENESIS (2001)
Evidence that furin is an authentic transforming growth factor-beta 1-converting enzyme
CM Dubois et al.
AMERICAN JOURNAL OF PATHOLOGY (2001)
Polyarginines are potent furin inhibitors
A Cameron et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Share Paper
