Journal
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume 57, Issue 33, Pages 10661-10665Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201806238
Keywords
allenes; asymmetric catalysis; chirality; furans; organocatalysis
Categories
Funding
- Carlsberg Foundations Semper Ardens
- FNU
- Aarhus University
- DNRS
- Chinese Scholarship Foundation
Ask authors/readers for more resources
A novel reaction that provides chiral allenes by amino catalytic activation of either aldehydes or alpha,beta-unsaturated aldehydes for reaction with alkynyl-substituted enones is presented. The reaction forms a variety of trisubstituted allenes in high yields and with excellent stereoselectivities. The utility of the reaction concept is demonstrated by the synthesis of chiral furan derivatives in high yields and stereoselectivities.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available