4.8 Article

Chiral DNA Origami Nanotubes with Well-Defined and Addressable Inside and Outside Surfaces

Journal

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume 57, Issue 26, Pages 7687-7690

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201800275

Keywords

chiral nanotubes; DNA nanotechnology; DNA self-assembly; molecular motors; plasmonic devices

Funding

  1. Biotechnology and Biological Sciences Research council [BB/J00054X/1]
  2. Engineering and Physical Sciences Research Council grant [EP/F500394/1]
  3. Royal Society Wolfson Research Merit Award
  4. BBSRC [BB/J00054X/1] Funding Source: UKRI

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We report the design and assembly of chiral DNA nanotubes with well-defined and addressable inside and outside surfaces. We demonstrate that the outside surface can be functionalised with a chiral arrangement of gold nanoparticles to create a plasmonic device and that the inside surface can be functionalised with a track for a molecular motor allowing transport of a cargo within the central cavity.

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