4.6 Article

Colorimetric detection of influenza A (H1N1) virus by a peptide-functionalized polydiacetylene (PEP-PDA) nanosensor

Journal

RSC ADVANCES
Volume 6, Issue 54, Pages 48566-48570

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c6ra06689e

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Funding

  1. National Research Foundation of Korea (NRF) grant - Ministry of Education, Science and Technology [NRF-2014M3A6B2060507, H-GUARD_2014M3A6B2060489]
  2. KRIBB Research Initiative Program of the Republic of Korea
  3. National Research Foundation of Korea [2014M3A6B2060507] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)

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We developed a peptide-functionalized polydiacetylene (PEP-PDA) nanosensor for pandemic H1N1 virus (pH1N1) detection with the naked eye. A PDA nanosensor was fabricated by nano-precipitation and modified with PEP for the specific recognition of pH1N1. The PEP-PDA nanosensor showed unique chromatic properties involving a colour change fromblue to red in the presence of pH1N1. We believe that this nanosensor can be applied for the development of a commercially available kit for pH1N1 detection.

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