Related references
Note: Only part of the references are listed.Serendipitous Discovery of a Potent Influenza Virus A Neuraminidase Inhibitor
Sankar Mohan et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2014)
High-throughput docking for the identification of new influenza A virus polymerase inhibitors targeting the PA-PB1 protein-protein interaction
Cristina Tintori et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2014)
Antiviral strategies against influenza virus: towards new therapeutic approaches
Arianna Loregian et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2014)
The Fight against the Influenza A Virus H1N1: Synthesis, Molecular Modeling, and Biological Evaluation of Benzofurazan Derivatives as Viral RNA Polymerase Inhibitors
Mafalda Pagano et al.
CHEMMEDCHEM (2014)
A review of neuraminidase inhibitor susceptibility in influenza strains
Nick Spanakis et al.
EXPERT REVIEW OF ANTI-INFECTIVE THERAPY (2014)
Novel oral anti-influenza drug candidate AV5080
Alexandre V. Ivachtchenko et al.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2014)
Phenyl Substituted 4-Hydroxypyridazin-3(2H)-ones and 5-Hydroxypyrimidin-4(3H)-ones: Inhibitors of Influenza A Endonuclease
Hye Yeon Sagong et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
Discovery of a Novel, First-in-Class, Orally Bioavailable Azaindole Inhibitor (VX-787) of Influenza PB2
Michael P. Clark et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
New Small Molecule Entry Inhibitors Targeting Hemagglutinin-Mediated Influenza A Virus Fusion
Arnab Basu et al.
JOURNAL OF VIROLOGY (2014)
The N-Terminal Domain of PA from Bat-Derived Influenza-Like Virus H17N10 Has Endonuclease Activity
Boris Tefsen et al.
JOURNAL OF VIROLOGY (2014)
Antiviral combinations for severe influenza
Jake Dunning et al.
LANCET INFECTIOUS DISEASES (2014)
An important amino acid in nucleoprotein contributes to influenza A virus replication by interacting with polymerase PB2
Xun Gui et al.
VIROLOGY (2014)
Emerging antiviral resistant strains of influenza A and the potential therapeutic targets within the viral ribonucleoprotein (vRNP) complex
Alicia M. Davis et al.
VIROLOGY JOURNAL (2014)
Segmented negative strand RNA virus nucleoprotein structure
Juan Reguera et al.
CURRENT OPINION IN VIROLOGY (2014)
Crystallographic Fragment Screening and Structure-Based Optimization Yields a New Class of Influenza Endonuclease Inhibitors
Joseph D. Bauman et al.
ACS CHEMICAL BIOLOGY (2013)
Structure-Based Discovery of the Novel Antiviral Properties of Naproxen against the Nucleoprotein of Influenza A Virus
Nathalie Lejal et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2013)
Design of inhibitors of influenza virus membrane fusion: Synthesis, structure-activity relationship and in vitro antiviral activity of a novel indole series
Virginia Brancato et al.
ANTIVIRAL RESEARCH (2013)
The influenza virus NS1 protein as a therapeutic target
Daniel A. Engel
ANTIVIRAL RESEARCH (2013)
Phenyl substituted 3-hydroxypyridin-2(1H)-ones: Inhibitors of influenza A endonuclease
Ajit K. Parhi et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2013)
A peptide derived from the C-terminus of PB1 inhibits influenza virus replication by interfering with viral polymerase assembly
Chunfeng Li et al.
FEBS JOURNAL (2013)
Influenza virus nucleoprotein: structure, RNA binding, oligomerization and antiviral drug target
Sylvie Chenavas et al.
FUTURE MICROBIOLOGY (2013)
New 7-Methylguanine Derivatives Targeting the Influenza Polymerase PB2 Cap-Binding Domain
Stephane Pautus et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
Nucleozin Targets Cytoplasmic Trafficking of Viral Ribonucleoprotein-Rab11 Complexes in Influenza A Virus Infection
Maria Joao Amorim et al.
JOURNAL OF VIROLOGY (2013)
Structural basis for encapsidation of genomic RNA by La Crosse Orthobunyavirus nucleoprotein
Juan Reguera et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Structure and inhibition of the drug-resistant S31N mutant of the M2 ion channel of influenza A virus
Jun Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
A functional sequence-specific interaction between influenza A virus genomic RNA segments
Cyrille Gavazzi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Mechanism-Based Covalent Neuraminidase Inhibitors with Broad-Spectrum Influenza Antiviral Activity
Jin-Hyo Kim et al.
SCIENCE (2013)
Structural and energetic analysis of drug inhibition of the influenza A M2 proton channel
Ruo-Xu Gu et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2013)
Biochemical and Structural Evidence in Support of a Coherent Model for the Formation of the Double-Helical Influenza A Virus Ribonucleoprotein
Qiaozhen Ye et al.
MBIO (2013)
3-Hydroxyquinolin-2(1H)-ones As Inhibitors of Influenza A Endonuclease
Hye Yeon Sagong et al.
ACS MEDICINAL CHEMISTRY LETTERS (2013)
Influenza neuraminidase operates via a nucleophilic mechanism and can be targeted by covalent inhibitors
Christopher J. Vavricka et al.
NATURE COMMUNICATIONS (2013)
The role and assembly mechanism of nucleoprotein in influenza A virus ribonucleoprotein complexes
Lauren Turrell et al.
NATURE COMMUNICATIONS (2013)
Structural basis for a class of nanomolar influenza A neuraminidase inhibitors
Philip S. Kerry et al.
SCIENTIFIC REPORTS (2013)
Monomeric Nucleoprotein of Influenza A Virus
Sylvie Chenavas et al.
PLOS PATHOGENS (2013)
Human Cytomegalovirus Inhibitor AL18 Also Possesses Activity against Influenza A and B Viruses
Giulia Muratore et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2012)
Oligomerization paths of the nucleoprotein of influenza A virus
B. Tarus et al.
BIOCHIMIE (2012)
Recent progress in structure-based anti-influenza drug design
Juan Du et al.
DRUG DISCOVERY TODAY (2012)
Design, Synthesis, and in Vitro Biological Evaluation of 1H-1,2,3-Triazole-4-carboxamide Derivatives as New Anti-influenza A Agents Targeting Virus Nucleoprotein
Huimin Cheng et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Antivirals Targeting Influenza A Virus
Kalyan Das
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Structural Basis for RNA Binding and Homo-Oligomer Formation by Influenza B Virus Nucleoprotein
Andy Ka-Leung Ng et al.
JOURNAL OF VIROLOGY (2012)
Sequence in the Influenza A Virus Nucleoprotein Required for Viral Polymerase Binding and RNA Synthesis
Jesper K. Marklund et al.
JOURNAL OF VIROLOGY (2012)
Molecular Dynamics Studies of the Nucleoprotein of Influenza A Virus: Role of the Protein Flexibility in RNA Binding
Bogdan Tarus et al.
PLOS ONE (2012)
Influenza Polymerase Activity Correlates with the Strength of Interaction between Nucleoprotein and PB2 through the Host-Specific Residue K/E627
Andy Ka-Leung Ng et al.
PLOS ONE (2012)
Polymer-attached zanamivir inhibits synergistically both early and late stages of influenza virus infection
Chia Min Lee et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Small molecule inhibitors of influenza A and B viruses that act by disrupting subunit interactions of the viral polymerase
Giulia Muratore et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
The Structure of Native Influenza Virion Ribonucleoproteins
Rocio Arranz et al.
SCIENCE (2012)
Organization of the Influenza Virus Replication Machinery
Arne Moeller et al.
SCIENCE (2012)
Emerging cellular targets for influenza antiviral agents
Konstantin H. Mueller et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2012)
Structural and Biochemical Basis for Development of Influenza Virus Inhibitors Targeting the PA Endonuclease
Rebecca M. DuBois et al.
PLOS PATHOGENS (2012)
Structural Analysis of Specific Metal Chelating Inhibitor Binding to the Endonuclease Domain of Influenza pH1N1 (2009) Polymerase
Eva Kowalinski et al.
PLOS PATHOGENS (2012)
Identification of Influenza Virus Inhibitors Targeting NS1A Utilizing Fluorescence Polarization-Based High-Throughput Assay
Eun Jeong Cho et al.
JOURNAL OF BIOMOLECULAR SCREENING (2012)
Synthesis and evaluation of quinoxaline derivatives as potential influenza NS1A protein inhibitors
Lei You et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2011)
Nucleoproteins and nucleocapsids of negative-strand RNA viruses
Rob W. H. Ruigrok et al.
CURRENT OPINION IN MICROBIOLOGY (2011)
Exploring the Size Limit of Templates for Inhibitors of the M2 Ion Channel of Influenza A Virus
Maria D. Duque et al.
JOURNAL OF MEDICINAL CHEMISTRY (2011)
Reversing chemoresistance by small molecule inhibition of the translation initiation complex eIF4F
Regina Cencic et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
E339 ... R416 salt bridge of nucleoprotein as a feasible target for influenza virus inhibitors
Yu-Fang Shen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Inhibition of influenza virus replication via small molecules that induce the formation of higher-order nucleoprotein oligomers
Samuel W. Gerritz et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Computational Design of Proteins Targeting the Conserved Stem Region of Influenza Hemagglutinin
Sarel J. Fleishman et al.
SCIENCE (2011)
Human importin alpha and RNA do not compete for binding to influenza A virus nucleoprotein
Sebastien Boulo et al.
VIROLOGY (2011)
Design and Synthesis of Benzenesulfonamide Derivatives as Potent Anti-Influenza Hemagglutinin Inhibitors
Guozhi Tang et al.
ACS MEDICINAL CHEMISTRY LETTERS (2011)
Structural and Functional Analysis of Laninamivir and its Octanoate Prodrug Reveals Group Specific Mechanisms for Influenza NA Inhibition
Christopher J. Vavricka et al.
PLOS PATHOGENS (2011)
Structure of the amantadine binding site of influenza M2 proton channels in lipid bilayers
Sarah D. Cady et al.
NATURE (2010)
Identification of influenza A nucleoprotein as an antiviral target
Richard Y. Kao et al.
NATURE BIOTECHNOLOGY (2010)
Structures of influenza A proteins and insights into antiviral drug targets
Kalyan Das et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2010)
Novel sialic acid derivatives lock open the 150-loop of an influenza A virus group-1 sialidase
Santosh Rudrawar et al.
NATURE COMMUNICATIONS (2010)
Characteristics of arbidol-resistant mutants of influenza virus: Implications for the mechanism of anti-influenza action of arbidol
Irina A. Leneva et al.
ANTIVIRAL RESEARCH (2009)
Structural insight into the essential PB1-PB2 subunit contact of the influenza virus RNA polymerase
Kanako Sugiyama et al.
EMBO JOURNAL (2009)
Interaction of the Influenza A Virus Nucleocapsid Protein with the Viral RNA Polymerase Potentiates Unprimed Viral RNA Replication
Laura L. Newcomb et al.
JOURNAL OF VIROLOGY (2009)
Crystal structure of an avian influenza polymerase PAN reveals an endonuclease active site
Puwei Yuan et al.
NATURE (2009)
The cap-snatching endonuclease of influenza virus polymerase resides in the PA subunit
Alexandre Dias et al.
NATURE (2009)
Identification of a PA-Binding Peptide with Inhibitory Activity against Influenza A and B Virus Replication
Kerstin Wunderlich et al.
PLOS ONE (2009)
The Structure of a Biologically Active Influenza Virus Ribonucleoprotein Complex
Rocio Coloma et al.
PLOS PATHOGENS (2009)
Treatment of influenza A (H1N1) virus infections in mice and ferrets with cyanovirin-N
Donald F. Smee et al.
ANTIVIRAL RESEARCH (2008)
Structure of the influenza virus A H5N1 nucleoprotein: implications for RNA binding, oligomerization, and vaccine design
Andy Ka-Leung Ng et al.
FASEB JOURNAL (2008)
Structure and mechanism of the M2 proton channel of influenza A virus
Jason R. Schnell et al.
NATURE (2008)
Crystal structure of the polymerase PAC-PB1N complex from an avian influenza H5N1 virus
Xiaojing He et al.
NATURE (2008)
The structural basis for an essential subunit interaction in influenza virus RNA polymerase
Eiji Obayashi et al.
NATURE (2008)
The structural basis for cap binding by influenza virus polymerase subunit PB2
Delphine Guilligay et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2008)
Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion
Rupert J. Russell et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Host determinant residue lysine 627 lies on the surface of a discrete, folded domain of influenza virus polymerase PB2 subunit
Franck Tarendeau et al.
PLOS PATHOGENS (2008)
Conserved surface features form the double-stranded RNA binding site of non-structural protein 1 (NS1) from influenza A and B viruses
Cuifeng Yin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Peptide-mediated interference with influenza A virus polymerase
Alexander Ghanem et al.
JOURNAL OF VIROLOGY (2007)
The mechanism by which influenza A virus nucleoprotein forms oligomers and binds RNA
Qiaozhen Ye et al.
NATURE (2006)
The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design
Rupert J. Russell et al.
NATURE (2006)
A single amino acid mutation in the PA subunit of the influenza virus RNA polymerase inhibits endonucleolytic cleavage of capped RNAs
E Fodor et al.
JOURNAL OF VIROLOGY (2002)
The RNA polymerase of influenza A virus is stabilized by interaction with its viral RNA promoter
GG Brownlee et al.
JOURNAL OF VIROLOGY (2002)
The influenza virus nucleoprotein: a multifunctional RNA-binding protein pivotal to virus replication
A Portela et al.
JOURNAL OF GENERAL VIROLOGY (2002)
Functional analysis of PA binding by influenza a virus PB1: Effects on polymerase activity and viral infectivity
DR Perez et al.
JOURNAL OF VIROLOGY (2001)