Journal
FRONTLINE GASTROENTEROLOGY
Volume 7, Issue 3, Pages 167-169Publisher
BMJ PUBLISHING GROUP
DOI: 10.1136/flgastro-2015-100672
Keywords
-
Categories
Funding
- ESRC [ES/K007688/1] Funding Source: UKRI
- MRC [MR/L001489/1, G0700718, MR/L016354/1] Funding Source: UKRI
- Alzheimer's Society [189] Funding Source: researchfish
- Economic and Social Research Council [ES/K007688/1] Funding Source: researchfish
- Medical Research Council [G0700718, MR/L016354/1, MR/L001489/1] Funding Source: researchfish
- National Institute for Health Research [SRF-2011-04-017, NF-SI-0513-10091] Funding Source: researchfish
- Medical Research Council [G0700718, MR/L001489/1, MR/L016354/1] Funding Source: Medline
- Department of Health [SRF-2011-04-017] Funding Source: Medline
- Alzheimer's Society [189] Funding Source: Medline
Ask authors/readers for more resources
Background It is being increasingly recognised that reduced cardiorespiratory fitness is associated with poorer outcomes after major surgery. Exercise limitation and reduced aerobic capacity are common in people with end-stage liver disease. There is limited evidence about the role of exercise therapy in the management of primary biliary cirrhosis (PBC) and no studies have looked at the effect of exercise in people with PBC who are awaiting liver transplantation. This case study is the first to report that personalised exercise therapy improves cardiorespiratory fitness in a patient with PBC without worsening symptoms of severe fatigue. Methods Cardiopulmonary exercise testing was used to assess cardiorespiratory fitness in a patient with end-stage PBC prior to listing for transplantation. A personalised exercise programme was designed to improve cardiorespiratory fitness while the patient was on the transplant waiting list. Results Anaerobic threshold, VO2PEAK and maximum workload all improved with regular exercise. Fatigue levels remained unaltered. Conclusions This patient tolerated and adhered to a personalised exercise programme for a prolonged period of time while awaiting surgery despite significant fatigue and disease burden. Liver transplantation was successfully completed and this woman remains well over 2 years post-surgery.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available