4.3 Article

The potential contribution of the natural products from Brazilian biodiversity to bioeconomy

Journal

ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS
Volume 90, Issue 1, Pages 763-778

Publisher

ACAD BRASILEIRA DE CIENCIAS
DOI: 10.1590/0001-3765201820170653

Keywords

Brazilian biodiversity; natural products; medicinal chemistry; database

Funding

  1. Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) [2013/07600-3]
  2. CIBFar
  3. CEPID [465637/2014-0]
  4. INCT BioNat CNPq/FAPESP [2013/07600-3]
  5. BIOTA-FAPESP grant [03/02176-7]
  6. SISBIOTA-CNPq-FAPESP grant [2010/52327-5]
  7. Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES)
  8. Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq)
  9. CNPq [167874/2014-4, 152243/2016-0, 152341/2015-2]

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The development of our society has been based on the use of biodiversity, especially for medicines and nutrition. Brazil is the nation with the largest biodiversity in the world accounting for more than 15% of all living species. The devastation of biodiversity in Brazil is critical and may not only cause the loss of species and genes that encode enzymes involved in the complex metabolism of organisms, but also the loss of a rich chemical diversity, which is a potential source for bioeconomy based on natural products and new synthetic derivatives. Bioeconomy focus on the use of bio-based products, instead of fossil-based ones and could address some of the important challenges faced by society. Considering the chemical and biological diversity of Brazil, this review highlights the Brazilian natural products that were successfully used to develop new products and the value of secondary metabolites from Brazilian biodiversity with potential application for new products and technologies. Additionally, we would like to address the importance of new technologies and scientific programs to support preservation policies, bioeconomy and strategies for the sustainable use of biodiversity.

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