Related references
Note: Only part of the references are listed.RP5063, a novel, multimodal, serotonin receptor modulator, prevents Sugen 5416-hypoxia induced pulmonary arterial hypertension in rats
Laxminarayan Bhat et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2017)
RP5063, a novel, multimodal, serotonin receptor modulator, prevents monocrotaline-induced pulmonary arterial hypertension in rats
Laxminarayan Bhat et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2017)
Cocktail of Superoxide Dismutase and Fasudil Encapsulated in Targeted Liposomes Slows PAH Progression at a Reduced Dosing Frequency
Nilesh Gupta et al.
MOLECULAR PHARMACEUTICS (2017)
Inhibition of pyruvate dehydrogenase kinase improves pulmonary arterial hypertension in genetically susceptible patients
Evangelos D. Michelakis et al.
SCIENCE TRANSLATIONAL MEDICINE (2017)
Estrogen receptor-dependent attenuation of hypoxia-induced changes in the lung genome of pulmonary hypertension rats
Andrea L. Frump et al.
PULMONARY CIRCULATION (2017)
Steps forward in the treatment of pulmonary arterial hypertension: latest developments and clinical opportunities
Jessica B. Badlam et al.
THERAPEUTIC ADVANCES IN CHRONIC DISEASE (2017)
HDAC6: A Novel Histone Deacetylase Implicated in Pulmonary Arterial Hypertension
Olivier Boucherat et al.
SCIENTIFIC REPORTS (2017)
Pharmacological Inhibition of mTOR Kinase Reverses Right Ventricle Remodeling and Improves Right Ventricle Structure and Function in Rats
Andressa Pena et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2017)
Hypermethylation of BMPR2 Promoter Occurs in Patients with Heritable Pulmonary Arterial Hypertension and Inhibits BMPR2 Expression
Dong Liu et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2017)
Endothelial Nox1 oxidase assembly in human pulmonary arterial hypertension; driver of Gremlin1-mediated proliferation
Imad Al Ghouleh et al.
CLINICAL SCIENCE (2017)
INDIE-HFpEF (Inorganic Nitrite Delivery to Improve Exercise Capacity in Heart Failure With Preserved Ejection Fraction): Rationale and Design
Yogesh N. V. Reddy et al.
CIRCULATION-HEART FAILURE (2017)
PPARγ Links BMP2 and TGFβ1 Pathways in Vascular Smooth Muscle Cells, Regulating Cell Proliferation and Glucose Metabolism
Laurent Calvier et al.
CELL METABOLISM (2017)
Elabela/Toddler Is an Endogenous Agonist of the Apelin APJ Receptor in the Adult Cardiovascular System, and Exogenous Administration of the Peptide Compensates for the Downregulation of Its Expression in Pulmonary Arterial Hypertension
Peiran Yang et al.
CIRCULATION (2017)
From Cancer Biology to New Pulmonary Arterial Hypertension Therapeutics Targeting Cell Growth and Proliferation Signaling Hubs
Soni Savai Pullamsettit et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2017)
Translating MicroRNA Biology in Pulmonary Hypertension It Will Take More Than miR Words
Hyung J. Chun et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2017)
Leukotriene B4 mediates macrophage influx and pulmonary hypertension in bleomycin-induced chronic neonatal lung injury
Mong Tieng Ee et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2016)
Histone deacetylation contributes to low extracellular superoxide dismutase expression in human idiopathic pulmonary arterial hypertension
Eva Nozik-Grayck et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2016)
HIPPO-Integrin-linked Kinase Cross-Talk Controls Self-Sustaining Proliferation and Survival in Pulmonary Hypertension
Tatiana V. Kudryashova et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2016)
A Selective Transforming Growth Factor-β Ligand Trap Attenuates Pulmonary Hypertension
Lai-Ming Yung et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2016)
Higher Estradiol and Lower Dehydroepiandrosterone-Sulfate Levels Are Associated with Pulmonary Arterial Hypertension in Men
Corey E. Ventetuolo et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2016)
Inhaled Sodium Nitrite Improves Rest and Exercise Hemodynamics in Heart Failure With Preserved Ejection Fraction
Barry A. Borlaug et al.
CIRCULATION RESEARCH (2016)
Up-regulation of the mammalian target of rapamycin complex 1 subunit Raptor by aldosterone induces abnormal pulmonary artery smooth muscle cell survival patterns to promote pulmonary arterial hypertension
Reza Aghamohammadzadeh et al.
FASEB JOURNAL (2016)
Inhibition of histone deacetylase reduces transcription of NADPH oxidases and ROS production and ameliorates pulmonary arterial hypertension
Feng Chen et al.
FREE RADICAL BIOLOGY AND MEDICINE (2016)
Reversal of right ventricular remodeling by dichloroacetate is related to inhibition of mitochondria-dependent apoptosis
Xiao-Qing Sun et al.
HYPERTENSION RESEARCH (2016)
A global view of pulmonary hypertension
Marius M. Hoeper et al.
LANCET RESPIRATORY MEDICINE (2016)
Serotonin 2B Receptor Antagonism Prevents Heritable Pulmonary Arterial Hypertension
James D. West et al.
PLOS ONE (2016)
Acute hemodynamic effects of inhaled sodium nitrite in pulmonary hypertension associated with heart failure with preserved ejection fraction
Marc A. Simon et al.
JCI INSIGHT (2016)
Hypoxia-induced glucose-6-phosphate dehydrogenase overexpression and -activation in pulmonary artery smooth muscle cells: implication in pulmonary hypertension
Sukrutha Chettimada et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2015)
Augmentation of the effects of vasoactive intestinal peptide aerosol on pulmonary hypertension via coapplication of a neutral endopeptidase 24.11 inhibitor
Hanno H. Leuchte et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2015)
Deficiency of Akt1, but not Akt2, attenuates the development of pulmonary hypertension
Haiyang Tang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2015)
Serotonin transporter is not required for the development of severe pulmonary hypertension in the Sugen hypoxia rat model
Michiel Alexander de Raaf et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2015)
Suppression of endothelial CD39/ENTPD1 is associated with pulmonary vascular remodeling in pulmonary arterial hypertension
Mikko H. Helenius et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2015)
The pathophysiology of pulmonary hypertension in left heart disease
Siegfried Breitling et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2015)
Low-Dose FK506 (Tacrolimus) in End-Stage Pulmonary Arterial Hypertension
Edda Spiekerkoetter et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2015)
Elafin Reverses Pulmonary Hypertension via Caveolin-1-Dependent Bone Morphogenetic Protein Signaling
Nils P. Nickel et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2015)
Initial Data Report from LARIAT: A Phase 2 Study of Bardoxolone Methyl in PAH Patients on Stable Background Therapy
Ronald Oudiz et al.
CHEST (2015)
Effects of the Rho-Kinase Inhibitor, Fasudil, on Pulmonary Hypertension
Keiichi Odagiri et al.
CIRCULATION JOURNAL (2015)
Acute Effects of Rho-Kinase Inhibitor Fasudil on Pulmonary Arterial Hypertension in Patients With Congenital Heart Defects
Jia-wang Xiao et al.
CIRCULATION JOURNAL (2015)
Long-term safety and efficacy of imatinib in pulmonary arterial hypertension
Adaani E. Frost et al.
JOURNAL OF HEART AND LUNG TRANSPLANTATION (2015)
Sodium Nitrite Improves Exercise Hemodynamics and Ventricular Performance in Heart Failure With Preserved Ejection Fraction
Barry A. Borlaug et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2015)
Intrinsic BMP Antagonist Gremlin-1 as a Novel Circulating Marker in Pulmonary Arterial Hypertension
Jasmin Wellbrock et al.
LUNG (2015)
Selective enhancement of endothelial BMPR-II with BMP9 reverses pulmonary arterial hypertension
Lu Long et al.
NATURE MEDICINE (2015)
Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Nebulized Sodium Nitrite (AIR001) Following Repeat-Dose Inhalation in Healthy Subjects
Peter J. Rix et al.
CLINICAL PHARMACOKINETICS (2015)
An ERK/Cdk5 axis controls the diabetogenic actions of PPARγ
Alexander S. Banks et al.
NATURE (2015)
Therapeutic Efficacy of Valproic Acid in a Combined Monocrotaline and Chronic Hypoxia Rat Model of Severe Pulmonary Hypertension
Beidi Lan et al.
PLOS ONE (2015)
Dehydroepiandrosterone promotes pulmonary artery relaxation by NADPH oxidation-elicited subunit dimerization of protein kinase G 1α
Dhara Patel et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2014)
The Sphingosine Kinase 1/Sphingosine-1-Phosphate Pathway in Pulmonary Arterial Hypertension
Jiwang Chen et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2014)
Protective Effects of 10-nitro-oleic Acid in a Hypoxia-Induced Murine Model of Pulmonary Hypertension
Anna Klinke et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2014)
Fatty acid nitroalkenes ameliorate glucose intolerance and pulmonary hypertension in high-fat diet-induced obesity
Eric E. Kelley et al.
CARDIOVASCULAR RESEARCH (2014)
Sirtuin 3 Deficiency Is Associated with Inhibited Mitochondrial Function and Pulmonary Arterial Hypertension in Rodents and Humans
Roxane Paulin et al.
CELL METABOLISM (2014)
Pharmacologic Therapy for Pulmonary Arterial Hypertension in Adults CHEST Guideline and Expert Panel Report
Darren B. Taichman et al.
CHEST (2014)
Advances in Therapeutic Interventions for Patients With Pulmonary Arterial Hypertension
Marc Humbert et al.
CIRCULATION (2014)
CCR5 as a Treatment Target in Pulmonary Arterial Hypertension
Valerie Amsellem et al.
CIRCULATION (2014)
Mammalian Target of Rapamycin Complex 2 ( mTORC2) Coordinates Pulmonary Artery Smooth Muscle Cell Metabolism, Proliferation, and Survival in Pulmonary Arterial Hypertension
Dmitry A. Goncharov et al.
CIRCULATION (2014)
Pulmonary Arterial Hypertension The Clinical Syndrome
Yen-Chun Lai et al.
CIRCULATION RESEARCH (2014)
Decreased levels of serum Angiotensin-(1-7) in patients with pulmonary arterial hypertension due to congenital heart disease
Hailong Dai et al.
INTERNATIONAL JOURNAL OF CARDIOLOGY (2014)
The MicroRNA 424/503 Cluster Reduces CDC25A Expression during Cell Cycle Arrest Imposed by Transforming Growth Factor β in Mammary Epithelial Cells
David Llobet-Navas et al.
MOLECULAR AND CELLULAR BIOLOGY (2014)
Dichloroacetate prevents but not reverses the formation of neointimal lesions in a rat model of severe pulmonary arterial hypertension
Bingbing Li et al.
MOLECULAR MEDICINE REPORTS (2014)
Apelin-APJ Signaling: a Potential Therapeutic Target for Pulmonary Arterial Hypertension
Jongmin Kim
MOLECULES AND CELLS (2014)
Pro-proliferative and inflammatory signaling converge on FoxO1 transcription factor in pulmonary hypertension
Rajkumar Savai et al.
NATURE MEDICINE (2014)
Rosiglitazone Attenuated Endothelin-1-Induced Vasoconstriction of Pulmonary Arteries in the Rat Model of Pulmonary Arterial Hypertension via Differential Regulation of ET-1 Receptors
Yahan Liu et al.
PPAR RESEARCH (2014)
Treatment with Anti-Gremlin 1 Antibody Ameliorates Chronic Hypoxia/SU5416-Induced Pulmonary Arterial Hypertension in Mice
Loredana Ciuclan et al.
AMERICAN JOURNAL OF PATHOLOGY (2013)
Dehydroepiandrosterone restores right ventricular structure and function in rats with severe pulmonary arterial hypertension
Abdallah Alzoubi et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2013)
Correction of Nonsense BMPR2 and SMAD9 Mutations by Ataluren in Pulmonary Arterial Hypertension
Kylie M. Drake et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2013)
Serotonin inhibits apoptosis of pulmonary artery smooth muscle cell by pERK1/2 and PDK through 5-HT1B receptors and 5-HT transporters
Ya Liu et al.
CARDIOVASCULAR PATHOLOGY (2013)
Imatinib Mesylate as Add-on Therapy for Pulmonary Arterial Hypertension Results of the Randomized IMPRES Study
Marius M. Hoeper et al.
CIRCULATION (2013)
Double-Blind, Placebo-Controlled Clinical Trial With a Rho-Kinase Inhibitor in Pulmonary Arterial Hypertension - A Pilot Efficacy Trial -
Yoshihiro Fukumoto et al.
CIRCULATION JOURNAL (2013)
Pathology of Pulmonary Hypertension
Rubin M. Tuder et al.
CLINICS IN CHEST MEDICINE (2013)
Plasma aldosterone levels are elevated in patients with pulmonary arterial hypertension in the absence of left ventricular heart failure: a pilot study
Bradley A. Maron et al.
EUROPEAN JOURNAL OF HEART FAILURE (2013)
Effect of Phosphodiesterase-5 Inhibition on Exercise Capacity and Clinical Status in Heart Failure With Preserved Ejection Fraction A Randomized Clinical Trial
Margaret M. Redfield et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2013)
FK506 activates BMPR2 rescues endothelial dysfunction, and reverses pulmonary hypertension
Edda Spiekerkoetter et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Updated Clinical Classification of Pulmonary Hypertension
Gerald Simonneau et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2013)
ACE2 Activation Confers Endothelial Protection and Attenuates Neointimal Lesions in Prevention of Severe Pulmonary Arterial Hypertension in Rats
Gang Li et al.
LUNG (2013)
An endothelial apelin-FGF link mediated by miR-424 and miR-503 is disrupted in pulmonary arterial hypertension
Jongmin Kim et al.
NATURE MEDICINE (2013)
Riociguat for the Treatment of Chronic Thromboembolic Pulmonary Hypertension
Hossein-Ardeschir Ghofrani et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
Riociguat for the Treatment of Pulmonary Arterial Hypertension
Hossein-Ardeschir Ghofrani et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
Vasodilatory Effect of the Stable Vasoactive Intestinal Peptide Analog RO 25-1553 in Murine and Rat Lungs
Jun Yin et al.
PLOS ONE (2013)
Long-term treatment with fasudil improves bleomycin-induced pulmonary fibrosis and pulmonary hypertension via inhibition of Smad2/3 phosphorylation
Yihua Bei et al.
PULMONARY PHARMACOLOGY & THERAPEUTICS (2013)
Blocking Macrophage Leukotriene B4 Prevents Endothelial Injury and Reverses Pulmonary Hypertension
Wen Tian et al.
SCIENCE TRANSLATIONAL MEDICINE (2013)
Everolimus in patients with severe pulmonary hypertension: a safety and efficacy pilot trial
Hans-Juergen Seyfarth et al.
PULMONARY CIRCULATION (2013)
Dehydroepiandrosterone (DHEA) improves pulmonary hypertension in chronic obstructive pulmonary disease (COPD): A pilot study
Eric Dumas de La Roque et al.
ANNALES D ENDOCRINOLOGIE (2012)
Cullin-3 Regulates Vascular Smooth Muscle Function and Arterial Blood Pressure via PPARγ and RhoA/Rho-Kinase
Christopher J. Pelham et al.
CELL METABOLISM (2012)
Gremlin Plays a Key Role in the Pathogenesis of Pulmonary Hypertension
Edwina Cahill et al.
CIRCULATION (2012)
Histone Deacetylation Inhibition in Pulmonary Hypertension Therapeutic Potential of Valproic Acid and Suberoylanilide Hydroxamic Acid
Lan Zhao et al.
CIRCULATION (2012)
Selective Class I Histone Deacetylase Inhibition Suppresses Hypoxia-Induced Cardiopulmonary Remodeling Through an Antiproliferative Mechanism
Maria A. Cavasin et al.
CIRCULATION RESEARCH (2012)
Molecular pathogenesis of pulmonary arterial hypertension
Marlene Rabinovitch
JOURNAL OF CLINICAL INVESTIGATION (2012)
Recombinant Angiotensin-Converting Enzyme 2 Suppresses Pulmonary Vasoconstriction in Acute Hypoxia
Axel Kleinsasser et al.
WILDERNESS & ENVIRONMENTAL MEDICINE (2012)
Dehydroepiandrosterone inhibits the Src/STAT3 constitutive activation in pulmonary arterial hypertension
Roxane Paulin et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2011)
Pulmonary Hypertension in Heart Failure With Preserved Ejection Fraction A Target of Phosphodiesterase-5 Inhibition in a 1-Year Study
Marco Guazzi et al.
CIRCULATION (2011)
C-122, a novel antagonist of serotonin receptor 5-HT2B, prevents monocrotaline-induced pulmonary arterial hypertension in rats
David A. Zopf et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2011)
mTOR is required for pulmonary arterial vascular smooth muscle cell proliferation under chronic hypoxia
Vera P. Krymskaya et al.
FASEB JOURNAL (2011)
Disruption of PPARγ/β-catenin-mediated regulation of apelin impairs BMP-induced mouse and human pulmonary arterial EC survival
Tero-Pekka Alastalo et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Epigenetic Mechanisms of Pulmonary Hypertension
Gene H. Kim et al.
Pulmonary Circulation (2011)
Rosiglitazone Attenuates Chronic Hypoxia-Induced Pulmonary Hypertension in a Mouse Model
Rachel E. Nisbet et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2010)
Nitrite Potently Inhibits Hypoxic and Inflammatory Pulmonary Arterial Hypertension and Smooth Muscle Proliferation via Xanthine Oxidoreductase-Dependent Nitric Oxide Generation
Brian S. Zuckerbraun et al.
CIRCULATION (2010)
Sodium Valproate, a Histone Deacetylase Inhibitor, but Not Captopril, Prevents Right Ventricular Hypertrophy in Rats
Young Kuk Cho et al.
CIRCULATION JOURNAL (2010)
Acute vasodilator effects of inhaled fasudil, a specific Rho-kinase inhibitor, in patients with pulmonary arterial hypertension
Hiroshi Fujita et al.
HEART AND VESSELS (2010)
Rosiglitazone attenuates hypoxia-induced pulmonary arterial hypertension in rats
Eun Kyung Kim et al.
RESPIROLOGY (2010)
Apelin decreases myocardial injury and improves right ventricular function in monocrotaline-induced pulmonary hypertension
Ines Falcao-Pires et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2009)
Pulmonary vasodilator responses to sodium nitrite are mediated by an allopurinol-sensitive mechanism in the rat
David B. Casey et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2009)
Tie2-mediated loss of peroxisome proliferator-activated receptor-γ in mice causes PDGF receptor-β-dependent pulmonary arterial muscularization
C. Guignabert et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2009)
Evidence for Angiotensin-converting Enzyme 2 as a Therapeutic Target for the Prevention of Pulmonary Hypertension
Anderson J. Ferreira et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2009)
Dichloroacetate treatment partially regresses established pulmonary hypertension in mice with SM22α-targeted overexpression of the serotonin transporter
Christophe Guignabert et al.
FASEB JOURNAL (2009)
Acute Inhibition of Rho-Kinase Attenuates Pulmonary Hypertension in Patients with Congenital Heart Disease
Fuhai Li et al.
PEDIATRIC CARDIOLOGY (2009)
Involvement of RhoA/Rho kinase signaling in protection against monocrotaline-induced pulmonary hypertension in pneumonectomized rats by dehydroepiandrosterone
Noriyuki Homma et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2008)
Genetic ablation of the Bmpr2 gene in pulmonary endothelium is sufficient to predispose to pulmonary arterial hypertension
Kwon-Ho Hong et al.
CIRCULATION (2008)
Inhalation of vasoactive intestinal peptide in pulmonary hypertension
H. H. Leuchte et al.
EUROPEAN RESPIRATORY JOURNAL (2008)
The nitrate-nitrite-nitric oxide pathway in physiology and therapeutics
Jon O. Lundberg et al.
NATURE REVIEWS DRUG DISCOVERY (2008)
Sildenafil improves exercise capacity and quality of life in patients with systolic heart failure and secondary pulmonary hypertension
Gregory D. Lewis et al.
CIRCULATION (2007)
Nitro-linoleic acid inhibits vascular smooth muscle cell proliferation via the Keap1/Nrf2 signaling pathway
Luis Villacorta et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2007)
Pulmonary arterial hypertension is linked to insulin resistance and reversed by peroxisome proliferator-activated receptor-γ activation
Georg Hansmann et al.
CIRCULATION (2007)
Nitrated fatty acids: Endogenous anti-inflammatory signaling mediators
Taixing Cui et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Bone morphogenetic protein receptor-2 signaling promotes pulmonary arterial endothelial cell survival - Implications for loss-of-function mutations in the pathogenesis of pulmonary hypertension
K Teichert-Kuliszewska et al.
CIRCULATION RESEARCH (2006)
BMPR2 Gene Rearrangements Account for a Significant Proportion of Mutations in Familial and Idiopathic Pulmonary Arterial Hypertension
Micheala A. Aldred et al.
HUMAN MUTATION (2006)
A variant of the gene encoding leukotriene A4 hydrolase confers ethnicity-specific risk of myocardial infarction
A Helgadottir et al.
NATURE GENETICS (2006)
Functional interactions between 5-hydroxytryptamine receptors and the serotonin transporter in pulmonary arteries
I Morecroft et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2005)
Nitrolinoleic acid:: An endogenous peroxisome proliferator-activated receptor γ ligand
FJ Schopfer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke
A Helgadottir et al.
NATURE GENETICS (2004)
Inhaled nebulized nitrite is a hypoxia-sensitive NO-dependent selective pulmonary vasodilator
CJ Hunter et al.
NATURE MEDICINE (2004)
Dichloroacetate prevents and reverses pulmonary hypertension by inducing pulmonary artery smooth muscle cell apoptosis
MS McMurtry et al.
CIRCULATION RESEARCH (2004)
Dehydroepiandrosterone (DHEA) prevents and reverses chronic hypoxic pulmonary hypertension
S Bonnet et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Peroxisome proliferator-activated receptor gamma (PPARγ) expression is decreased in pulmonary hypertension and affects endothelial cell growth
S Ameshima et al.
CIRCULATION RESEARCH (2003)
Expanding expression of the 5-lipoxygenase pathway within the arterial wall during human atherogenesis
R Spanbroek et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Sildenafil for treatment of lung fibrosis and pulmonary hypertension: a randomised controlled trial
HA Ghofrani et al.
LANCET (2002)
Dichloroacetate, a metabolic modulator, prevents and reverses chronic hypoxic pulmonary hypertension in rats - Role of increased expression and activity of voltage-gated potassium channels
ED Michelakis et al.
CIRCULATION (2002)
Rho-kinase as a novel therapeutic target in treatment of cardiovascular diseases
H Shimokawa
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2002)
Possible involvement of Rho-kinase in the pathogenesis of hypertension in humans
A Masumoto et al.
HYPERTENSION (2001)
Molecular properties of apelin: tissue distribution and receptor binding
Y Kawamata et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2001)