4.7 Review

Zebrafish dives into food research: effectiveness assessment of bioactive compounds

Journal

FOOD & FUNCTION
Volume 7, Issue 6, Pages 2615-2623

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c6fo00046k

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Funding

  1. Basque Government funding
  2. Fundacion Inaki Goenaga - Centros Tecnologicos
  3. Economic Development and Competitiveness Department of the Basque Government

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Zebrafish have been traditionally used in ecotoxicology and developmental biology. However, due to the advances in available methodologies and the similitude with mammals, it has been increasingly used in other fields. One of the most recent fields using zebrafish is food research, being the focus of this review. Most relevant and recent publications including food component toxicity and key metabolic effects together with effectiveness on some zebrafish disease models have been reviewed. This model is a good intermediate tool between in vitro and rodent models, because it provides information from a complete organism in a fast and cost-effective manner. Definitely, in the near future, we will see this model being used by the ingredient suppliers and scientists in order to show the potential impact on health of several compounds.

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