Journal
AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY
Volume 26, Issue 10, Pages 1091-1094Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.jagp.2018.06.006
Keywords
Executive dysfunction; late-life depression; geriatric; cognition; Trail Making Test; self-report
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Funding
- NIMH [KOS MH081065-01, NIMH RO1 MH09806201A1, NIMH RO1 MH101472-01A1]
- University of California, San Francisco, Leon Epstein Fund
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Objective: Prior work suggests executive dysfunction (ED) on the Stroop Color and Word Test (SCWT) and the Mattis Dementia Rating Scale-2 Initiation/Perseveration subscale (DRS IP) predicts poor antidepressant response in late-life depression. This study examined if either patient perception of ED or the Trail Making Test Part B (TMT-B) could identify patients with impairment on the SCWT or DRS IP. Methods: Patients were 65 or older and had a diagnosis of major depression without dementia. Cognition was assessed with the TMT-B, the SCWT, and the DRS IP. A self-reported Perceived Deficits Questionnaire (PDQ) subscale assessed patients' perceptions of ED. Results: In 247 participants (mean age 71.3 years), the PDQ subscale was not associated with test performance. The sensitivity of the TMT-B in identifying impairment on the SCWT or DRS IP was low (35% and 23%, respectively). Conclusion: Neither the TMTB nor self-reports are useful screening tools for ED on the SCWT or DRS IP.
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