An Adaptation of Anfinsen's Protein-Folding Experiment for Classroom Investigation

The study adapts Anfinsen's Nobel-winning experiment of protein folding into biology investigation for secondary and college students. This experiment is significant for secondary and college science learning not only for its associations with some core concepts in biology, but also for its rich nature of science and science practices. The lab procedure of the original experiment was modified to be accessible to secondary biology teachers and students. A detailed lab manual and task sheet are available.