Journal
ALZHEIMERS & DEMENTIA
Volume 14, Issue 3, Pages 280-292Publisher
WILEY
DOI: 10.1016/j.jalz.2017.09.007
Keywords
Vascular cognitive impairment; Vascular dementia; Guidelines; Criteria; consensus; Delphi
Categories
Funding
- Alzheimer's Society (UK) [Ref117]
- Pfizer
- Athersys
- AstraZeneca
- Lundbeck
- Cerevast
- Daiichi Sankyo
- Boehringer Ingelheim
- GE Healthcare
- TauRx
- Cytox
- Avid/Lilly
- Takeda
- Eli Lilly
- Elan/Transition Therapeutics
- Roche
- Cognoptix
- Eisai
- Novartis
- Alzheimers Research UK [ARUK-PG2013-22] Funding Source: researchfish
- Alzheimer's Society [117] Funding Source: researchfish
- Medical Research Council [G0900652, MR/L023784/1, G0502157, G0400074, G0500247, G1100540] Funding Source: researchfish
- MRC [G0400074, G0502157, MC_PC_18025, G0900652, G1100540, MR/M024784/1, G0500247, MR/L023784/1, MC_PC_14095] Funding Source: UKRI
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Introduction: Progress in understanding and management of vascular cognitive impairment (VCI) has been hampered by lack of consensus on diagnosis, reflecting the use of multiple different assessment protocols. A large multinational group of clinicians and researchers participated in a two-phase Vascular Impairment of Cognition Classification Consensus Study (VICCCS) to agree on principles (VICCCS-1) and protocols (VICCCS-2) for diagnosis of VCI. We present VICCCS-2. Methods: We used VICCCS-1 principles and published diagnostic guidelines as points of reference for an online Delphi survey aimed at achieving consensus on clinical diagnosis of VCI. Results: Six survey rounds comprising 65-79 participants agreed guidelines for diagnosis of VICCCS-revised mild and major forms of VCI and endorsed the National Institute of Neurological Disorders-Canadian Stroke Network neuropsychological assessment protocols and recommendations for imaging. Discussion: The VICCCS-2 suggests standardized use of the National Institute of Neurological Disorders-Canadian Stroke Network recommendations on neuropsychological and imaging assessment for diagnosis of VCI so as to promote research collaboration. (C) 2017 the Alzheimer's Association. Published by Elsevier Inc. All rights reserved.
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