4.0 Article

Emergence of Circulating Recombinant Form 56_cpx in Pakistan

Journal

AIDS RESEARCH AND HUMAN RETROVIRUSES
Volume 34, Issue 11, Pages 1002-1004

Publisher

MARY ANN LIEBERT, INC
DOI: 10.1089/aid.2018.0128

Keywords

HIV-1; CRF 56_cpx; drug resistance; Pakistan

Funding

  1. Aga Khan University Seed Money [PF84/0716]
  2. Higher Education Commission [HEC-5217]

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In Pakistan, HIV has converted from outbreak to concentrated epidemic and has also bridged into the low-risk population. The HIV epidemic in Pakistan mainly comprises subtype A. Here, we present the first case and genetic analysis of a circulating recombinant form 56_cpx in a Pakistani HIV-infected patient. Genetic analysis of the sequence indicated that Pakistani 56_cpx sequence had more drug resistance mutation than the other 56_cpx sequences available in the database.

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