Journal
EXPERIMENTAL GERONTOLOGY
Volume 72, Issue -, Pages 124-128Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.exger.2015.09.021
Keywords
Stress response; Senescence; Apoptosis; Stein cells
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Funding
- Russian Federal Agency of Scientific Organizations
- Russian Science Foundation [14-50-00068]
- Russian Science Foundation [14-50-00068] Funding Source: Russian Science Foundation
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Cellular senescence was initially described as the phenomenon of limited cell divisions that normal cells in culture can undergo during long-term-cultivation. Later it was found that senescence inay be induced by various stress factors. The intriguing resemblance between stress-induced and replicative senescence nukes questionable the distinction between both types and suggests that the cellular senescence is a common outcome of stress response. Growing evidences support the idea that stress-induced senescence is the cell-type specific. (C) 2015 Elsevier Inc. All rights reserved.
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