4.1 Article Data Paper

Data correlations between gender, cytomegalovirus infection and T cells, NK cells, and soluble immune mediators in elderly humans

Journal

DATA IN BRIEF
Volume 8, Issue -, Pages 536-544

Publisher

ELSEVIER SCIENCE BV
DOI: 10.1016/j.dib.2016.06.006

Keywords

NK cell; Ageing; Cytomegalovirus; T cell; Sex factors; Vitamin D; C-reactive protein; Adiponectin; IL-15; Sphingosine-1-phosphate; Retinol binding protein-4

Funding

  1. NIH [AG040542]
  2. University of Kentucky Center for Clinical and Translational Science Analytics Lab
  3. CTSA [UL1TR000117]

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We describe a cohort of 50 elderly subjects, age at least 70 years. We present gender-specific findings in T lymphocyte markers and soluble immune mediators. We show the correlation between cytomegalovirus infection status with CD56(dim) NK cell responses to a variety of stimuli and with CD56(bright)/CD56(dim) NK cell ratio. We also present the correlation of retinol binding protein (RBP) 4 plasma levels with NK cell responses and we explore the relationship between gender and adiponectin, 25(OH)D (vitamin D), and RBP4 in affecting CD56(dim) NK cell responses. These data are discussed in Al-Attar et al. (2016) [1]. (C) 2015 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/40).

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