4.8 Review

Advances in Biomaterials for Drug Delivery

Journal

ADVANCED MATERIALS
Volume 30, Issue 29, Pages -

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201705328

Keywords

biomaterials; drug delivery; immune therapy; nanomedicine; polymers

Funding

  1. Burroughs Wellcome Fund [1015145]
  2. Burroughs Wellcome Fund Career Award at the Scientific Interface
  3. NIH F32 Fellowship [CA200351]

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Advances in biomaterials for drug delivery are enabling significant progress in biology and medicine. Multidisciplinary collaborations between physical scientists, engineers, biologists, and clinicians generate innovative strategies and materials to treat a range of diseases. Specifically, recent advances include major breakthroughs in materials for cancer immunotherapy, autoimmune diseases, and genome editing. Here, strategies for the design and implementation of biomaterials for drug delivery are reviewed. A brief history of the biomaterials field is first established, and then commentary on RNA delivery, responsive materials development, and immunomodulation are provided. Current challenges associated with these areas as well as opportunities to address long-standing problems in biology and medicine are discussed throughout.

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