Journal
EXPERIMENTAL BIOLOGY AND MEDICINE
Volume 240, Issue 11, Pages 1387-1395Publisher
SAGE PUBLICATIONS LTD
DOI: 10.1177/1535370215576313
Keywords
Parkinson's disease; neuroinflammation; inflammation; disease models
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Funding
- NIH INBRE Program [P20 GM103408]
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Parkinson's disease (PD) is the first and second most prevalent motor and neurodegenerative disease, respectively. The clinical symptoms of PD result from a loss of midbrain dopaminergic (DA) neurons. However, the molecular cause of DA neuron loss remains elusive. Mounting evidence implicates enhanced inflammatory response in the development and progression of PD pathology. This review examines current research connecting PD and inflammatory response.
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