Journal
EXPERIMENTAL AND MOLECULAR PATHOLOGY
Volume 99, Issue 3, Pages 533-536Publisher
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.yexmp.2015.07.004
Keywords
Lymphoma; Leukemia; Mice; Mouse tumor biology database; Digital slides; Virtual slides
Categories
Funding
- National Institutes of Health [CA089713]
- Intramural Research Program of the NIH, NIAID
- Basic Cancer Center Core Grant from the National Cancer Institute [CA034196]
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Many mouse models have been created to study hematopoietic cancer types. There are over thirty hematopoietic tumor types and subtypes, both human and mouse, with various origins, characteristics and clinical prognoses. Determining the specific type of hematopoietic lesion produced in a mouse model and identifying mouse models that correspond to the human subtypes of these lesions has been a continuing challenge for the scientific community. The Mouse Tumor Biology Database (MTB; http://tumor.informatics.jax.org) is designed to facilitate use of mouse models of human cancer by providing detailed histopathologic and molecular information on lymphoma subtypes, including expertly annotated, on line, whole slide scans, and providing a repository for storing information on and querying these data for specific lymphoma models. (C) 2015 Elsevier Inc. All rights reserved.
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