Journal
JOURNAL OF EXERCISE REHABILITATION
Volume 12, Issue 5, Pages 380-385Publisher
KOREAN SOC EXERCISE REHABILITATION
DOI: 10.12965/jer.1632808.404
Keywords
Adult hippocampal neurogenesis; Neural plasticity; Neurotrophic factors; Cognitive decline; Exercise
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Funding
- 2014 Research Grant of Sangmyung University
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The functions of adult hippocampal neurogenesis have been extensively investigated during the past decade. Numerous studies have shown that adult neurogenesis may play an important role in the hippocampal-dependent learning and memory. This study evaluated the influence of exercise on hippocampal neurogenesis, neural plasticity, neurotrophic factors, and cognition. Areas of research focused on enhancing effect of exercise for adult hippocampal neurogenesis and protective role of exercise against brain diseases. The present study suggests that exercise improves brain functions and prevents decline of cognition across the lifespan. Understanding of neurobiological mechanisms of exercise on brain functions may lead to the development of novel therapeutic strategy for neurodegenerative disorders.
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